Open Access

The NLRP3 inflammasome in viral infection (Review)

  • Authors:
    • Qiaoli Zheng
    • Chunting Hua
    • Qichang Liang
    • Hao Cheng
  • View Affiliations

  • Published online on: July 6, 2023     https://doi.org/10.3892/mmr.2023.13047
  • Article Number: 160
  • Copyright: © Zheng et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The interplay between pathogen and host determines the immune response during viral infection. The Nod‑like receptor (NLR) protein 3 inflammasome is a multiprotein complex that induces the activation of inflammatory caspases and the release of IL‑1β, which play an important role in the innate immune responses. In the present review, the mechanisms of the NLR family pyrin domain containing 3 inflammasome activation and its dysregulation in viral infection were addressed.
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September-2023
Volume 28 Issue 3

Print ISSN: 1791-2997
Online ISSN:1791-3004

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Copy and paste a formatted citation
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Spandidos Publications style
Zheng Q, Hua C, Liang Q and Cheng H: The NLRP3 inflammasome in viral infection (Review). Mol Med Rep 28: 160, 2023.
APA
Zheng, Q., Hua, C., Liang, Q., & Cheng, H. (2023). The NLRP3 inflammasome in viral infection (Review). Molecular Medicine Reports, 28, 160. https://doi.org/10.3892/mmr.2023.13047
MLA
Zheng, Q., Hua, C., Liang, Q., Cheng, H."The NLRP3 inflammasome in viral infection (Review)". Molecular Medicine Reports 28.3 (2023): 160.
Chicago
Zheng, Q., Hua, C., Liang, Q., Cheng, H."The NLRP3 inflammasome in viral infection (Review)". Molecular Medicine Reports 28, no. 3 (2023): 160. https://doi.org/10.3892/mmr.2023.13047