Open Access

Angiogenesis signaling in endometriosis: Molecules, diagnosis and treatment (Review)

  • Authors:
    • Caixia Bo
    • Yunfei Wang
  • View Affiliations

  • Published online on: January 18, 2024     https://doi.org/10.3892/mmr.2024.13167
  • Article Number: 43
  • Copyright: © Bo et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY_NC 4.0].

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Abstract

Endometriosis (EM) is one of the most common diseases among women of reproductive age. The etiology and pathogenesis of EM remain unclear and therefore there is a lack of effective treatment measures, which affects physical and mental health, as well as the quality of life of patients with EM. Angiogenesis has become a hotspot for research on the pathogenesis of EM; the role of angiogenesis‑related serological markers and anti‑angiogenic therapy in the diagnosis and treatment of EM is promising for early diagnosis and treatment of EM. Angiogenesis in EM is subject to complex regulation by hormones, immunity and associated cytokines. Therefore, novel targets for angiogenesis therapy are also being discovered and developed. The present review summarized the pathological mechanisms of angiogenesis and the value of relevant markers in pathogenesis and diagnosis of EM, along with the status of research on anti‑angiogenic drugs in the treatment of EM. The role of angiogenesis in EM provides an important reference for treatment and diagnosis, but there is no uniform non‑invasive diagnostic marker and proven strategy for anti‑angiogenesis.
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March-2024
Volume 29 Issue 3

Print ISSN: 1791-2997
Online ISSN:1791-3004

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Spandidos Publications style
Bo C and Wang Y: Angiogenesis signaling in endometriosis: Molecules, diagnosis and treatment (Review). Mol Med Rep 29: 43, 2024.
APA
Bo, C., & Wang, Y. (2024). Angiogenesis signaling in endometriosis: Molecules, diagnosis and treatment (Review). Molecular Medicine Reports, 29, 43. https://doi.org/10.3892/mmr.2024.13167
MLA
Bo, C., Wang, Y."Angiogenesis signaling in endometriosis: Molecules, diagnosis and treatment (Review)". Molecular Medicine Reports 29.3 (2024): 43.
Chicago
Bo, C., Wang, Y."Angiogenesis signaling in endometriosis: Molecules, diagnosis and treatment (Review)". Molecular Medicine Reports 29, no. 3 (2024): 43. https://doi.org/10.3892/mmr.2024.13167