Open Access

Role of bariatric surgery in improving diabetic cardiomyopathy: Molecular mechanisms and therapeutic perspectives (Review)

  • Authors:
    • Ke Song
    • Dianyuan Liang
    • Dingqi Xiao
    • Aijia Kang
    • Yixing Ren
  • View Affiliations

  • Published online on: September 6, 2024     https://doi.org/10.3892/mmr.2024.13323
  • Article Number: 199
  • Copyright: © Song et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Diabetic cardiomyopathy (DCM), a significant complication of diabetes mellitus, is marked by myocardial structural and functional alterations due to chronic hyperglycemia. Despite its clinical significance, optimal treatment strategies are still elusive. Bariatric surgery via sleeve gastrectomy and Roux-en-Y gastric bypass have shown promise in treating morbid obesity and associated metabolic disorders including improvements in diabetes mellitus and DCM. The present study reviews the molecular mechanisms by which bariatric surgery improves DCM, offering insights into potential therapeutic targets. Future research should further investigate the mechanistic links between bariatric surgery and DCM, to evaluate the benefits and limitations of these surgical interventions for DCM treatment. The present study aims to provide a foundation for more effective DCM therapies, contributing to the advancement of patient care.
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November-2024
Volume 30 Issue 5

Print ISSN: 1791-2997
Online ISSN:1791-3004

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Copy and paste a formatted citation
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Spandidos Publications style
Song K, Liang D, Xiao D, Kang A and Ren Y: Role of bariatric surgery in improving diabetic cardiomyopathy: Molecular mechanisms and therapeutic perspectives (Review). Mol Med Rep 30: 199, 2024.
APA
Song, K., Liang, D., Xiao, D., Kang, A., & Ren, Y. (2024). Role of bariatric surgery in improving diabetic cardiomyopathy: Molecular mechanisms and therapeutic perspectives (Review). Molecular Medicine Reports, 30, 199. https://doi.org/10.3892/mmr.2024.13323
MLA
Song, K., Liang, D., Xiao, D., Kang, A., Ren, Y."Role of bariatric surgery in improving diabetic cardiomyopathy: Molecular mechanisms and therapeutic perspectives (Review)". Molecular Medicine Reports 30.5 (2024): 199.
Chicago
Song, K., Liang, D., Xiao, D., Kang, A., Ren, Y."Role of bariatric surgery in improving diabetic cardiomyopathy: Molecular mechanisms and therapeutic perspectives (Review)". Molecular Medicine Reports 30, no. 5 (2024): 199. https://doi.org/10.3892/mmr.2024.13323