Cribriform adenocarcinoma of the base of the tongue and low-grade, polymorphic adenocarcinomas of the salivary glands
- Authors:
- Aleš Čoček
- Klára Hronková
- Jana Voldánová
- Josef Šach
- Alena Skálová
- Miloslav Ambruš
- Jana Vránová
- Aleš Hahn
View Affiliations
Affiliations: Department of Otorhinolaryngology, Third Faculty of Medicine, Charles University in Prague, Faculty Hospital Královské Vinohrady, 10034, Prague 10, Czech Republic, Department of Pathology, Third Faculty of Medicine, Charles University in Prague, Faculty Hospital Královské Vinohrady, 10034, Prague 10, Czech Republic, Laboratory of Biopsy, Ltd., Pilsen, Czech Republic, Department of Radiotherapy and Oncology, Third Faculty of Medicine, Charles University in Prague, Faculty Hospital Královské Vinohrady, 10034, Prague 10, Czech Republic, Department of Medical Biophysics and Medical Informatics, Third Faculty of Medicine, Charles University in Prague, Faculty Hospital Královské Vinohrady, 10034, Prague 10, Czech Republic
- Published online on: November 23, 2010 https://doi.org/10.3892/ol.2010.213
-
Pages:
135-138
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Abstract
Low-grade, polymorphic adenocarcinomas occur mainly in females and are usually associated with the small salivary glands of the palate. The tumors are malignant, but not aggressive. Regional neck as well as distant metastasis is rare and the mortality rate is low. Cribriform adenocarcinoma of the salivary glands is a rare tumor, currently ranked among low-grade, polymorphic adenocarcinomas of the salivary glands. However, it differs from carcinomas in this group as it metastasizes to the cervical lymph nodes and exhibits frequent primary localization in the small salivary glands at the base of the tongue. Despite the tendency to metastasize, patient prognosis remains favorable. A case of a 72-year-old woman with neck metastases of cribriform adenocarcinoma, of unknown primary origin, is reported. The primary tumor origin was ultimately determined using nuclear magnetic resonance, histological verification was difficult due to the presence of an intact mucosal cover over the tumor. Cribriform adenocarcinoma is known to have a number of characteristics in common with a typical low-grade, salivary gland adenocarcinoma. However, in contrast to low-grade adenocarcinomas, the tumor presented with neck lymph node metastasis.
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View References
|
1
|
Batsakis JG, Pinkston GR, Luna M, et al:
Adenocarcinomas of the oral cavity: a clinicopathologic study of
terminal duct carcinomas. J Laryngol Otol. 97:825–835. 1983.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Evans HL and Batsakis JG: Polymorphous
low-grade adenocarcinoma of minor salivary glands: a study of 14
cases of a distinctive neoplasm. Cancer. 53:935–942. 1984.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Ellis GL and Auclair PL: Tumors of the
salivary glands. Atlas of Tumor Pathology. Ellis GL: AFIP;
Washington, DC: pp. 216–228. 1996
|
|
4
|
Michal M, Skálová A, Simpson RH, et al:
Cribriform adenocarcinoma of the tongue: a hitherto unrecognized
type of adenocarcinoma characteristically occurring in the tongue.
Histopathology. 35:495–501. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Perez-Ordonez B, Linkov I and Huvos AG:
Polymorphous low-grade adenocarcinome of minor salivary glands: a
study of 17 causes with emphasis on cell differentiation.
Histopathology. 32:521–529. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Wenig BM and Gnepp DR: Polymorphous
low-grade adenocarcinoma of minor salivary glands. Surgical
Pathology of the Salivary Glands. Ellis GL, Auclair PL and Gnepp
DR: Saunderes; Philadelphia: pp. 390–411. 1999
|
