Retroperitoneal primary mucinous adenocarcinoma: A case report

Jiang,Haiping; Jin,Ketao; You,Qihan; Fang,Weijia; Xu,Nong

doi:10.3892/ol.2011.319

Retroperitoneal primary mucinous adenocarcinoma: A case report

Authors:
- Haiping Jiang
- Ketao Jin
- Qihan You
- Weijia Fang
- Nong Xu
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Affiliations: Department of Internal Oncology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China, Department of Surgical Oncology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China, Department of Pathology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China, Department of Internal Oncology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China
Published online on: May 16, 2011 https://doi.org/10.3892/ol.2011.319
Pages: 633-636

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Abstract

Retroperitoneal primary mucinous adenocarcinoma (RPMA) is extremely rare and the histogenesis of this tumor remains unclear. There is no consensus on the appropriate treatment for RPMA. Surgical resection is standard for the treatment of RPMA, whereas the benefits of chemotherapy with regard to this tumor remain to be established. This case report concerns a 21-year-old female individual with RPMA. The patient initially presented with chronic lower back pain and weight loss. Additionally, carcinoembryonic antigen (CEA) levels were found to be elevated. A computed tomography scan revealed a mass in the abdominal cavity. Consequently, laparotomy was performed, which revealed a well-defined tumor in the right retroperitoneum. Chemotherapy as a monotherapy was not considered as a viable treatment option. Therefore, the patient was initially administered a combined treatement of oxaliplatin and 5-fluorouracil. This treatment was then changed to paclitaxel and 5-fluorouracil. Findings showed a decrease in the CEA serum levels, indicating that this combination treatment may be efficacious in the treatment of RPMA since local recurrence following surgical resection was well controlled with chemotherapy.

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1	Roth LM and Ehrlich CE: Mucinous cystadenocarcinoma of the retroperitoneum. Obstet Gynecol. 49:486–488. 1977.PubMed/NCBI
2	Papadogiannakis N, Gad A and Ehliar B: Primary retroperitoneal mucinous tumor of low malignant potential: histogenetic aspects and review of the literature. Acta Pathol Microbiol Immunol Scand Suppl. 105:483–486. 1997. View Article : Google Scholar : PubMed/NCBI
3	Thorbeck VC, Gustein D, Salvi M and Plata J: Retroperitoneal enteroid cystadenocarcinoma (possible intestinal origin). Rev Esp Enferm Apar Dig (In Spanish). 66:329–334. 1984.PubMed/NCBI
4	Kessler TM, Kessler W, Neuweiler J and Nachbur BH: Treatment of a case of primary retroperitoneal mucinous cyst-adenocarcinoma: is adjuvant hysterectomy and bilateral salpingo-oophorectomy justified? Am J Obstet Gynecol. 187:227–232. 2002. View Article : Google Scholar : PubMed/NCBI
5	De León DC, Pérez-Montiel D, Chanona-Vilchis J, Dueñas-González A, Villavicencio-Valencia V and Zavala-Casas G: Primary retroperitoneal mucinous cystadenocarcinoma: report of two cases. World J Surg Oncol. 5:52007.PubMed/NCBI
6	Subramony C, Habibpour S and Hashimoto LA: Retroperitoneal mucinous cystadenoma. Arch Pathol Lab Med. 125:691–694. 2001.
7	Green JM, Bruner BC, Tang WW and Orihuela E: Retroperitoneal mucinous cystadenocarcinoma in a man: case report and review of the literature. Urol Oncol. 25:53–55. 2007. View Article : Google Scholar : PubMed/NCBI
8	Thamboo TP, Sim R, Tan SY and Yap WM: Primary retroperitoneal mucinous cystadenocarcinoma in a male patient. J Clin Pathol. 59:655–657. 2006. View Article : Google Scholar : PubMed/NCBI
9	Motoyama T, Chida T, Fujiwara T and Watanabe H: Mucinous cystic tumor of the retroperitoneum: a report of two cases. Acta Cytol. 38:261–266. 1994.PubMed/NCBI
10	Hrora A, Reggoug S, Jallal H, Sabbah F, Benamer A, Alaoui M, Raiss M and Ahallat M: Primary retroperitoneal mucinous cyst-adenocarcinoma in a male patient: a case report. Cases Journal. 2:71962009. View Article : Google Scholar : PubMed/NCBI
11	Tangjitgamol S, Manusirivithaya S, Sheanakul C, Leelahakorn S, Thawaramsara T and Kaewpila N: Retroperitoneal mucinous cystadenocarcinoma: A case report and review of literature. Int J Gynecol Cancer. 12:403–408. 2002. View Article : Google Scholar
12	Matsubara M, Shiozawa T, Tachibana R, Hondo T, Osasda K, Kawaguchi K, Kimura K and Konishi I: Primary retroperitoneal mucinous cystadenoma of borderline malignancy: a case report and review of the literature. Int J Gynecol Pathol. 24:218–223. 2005. View Article : Google Scholar : PubMed/NCBI
13	Yang DM, Jung DH, Kim H, Kang JH, Kim SH, Kim JH and Hwang HY: Retroperitoneal cystic masses: CT, clinical, and pathological findings and literature review. Radiographics. 24:1353–1365. 2004. View Article : Google Scholar : PubMed/NCBI
14	Lee IW, Ching KC, Pang M and Ho TH: Two cases of primary retroperitoneal mucinous cystadenocarcinoma. Gynecol Oncol. 63:145–150. 1996. View Article : Google Scholar : PubMed/NCBI
15	Law KS, Chang TM and Tung JN: Fertility-sparing treatment of a primary retroperitoneal mucinous cystadenocarcinoma. BJOG. 113:612–614. 2006. View Article : Google Scholar : PubMed/NCBI
16	Lee SA, Bae SH, Ryoo HM, Jung HY, Jang SB and Kum YS: Primary retroperitoneal mucinous cystadenocarcinoma: a case report and review of the literature. Korean J Intern Med. 22:287–291. 2007. View Article : Google Scholar : PubMed/NCBI
17	Tenti P, Carnevali L, Tateo S and Durola R: Primary mucinous cystadeno-carcinoma of retroperitoneum: Two cases. Gynecol Oncol. 55:308–312. 1994. View Article : Google Scholar