Transitional cell carcinoma of the ovary (Review)

Ichigo,Satoshi; Takagi,Hiroshi; Matsunami,Kazutoshi; Murase,Takayuki; Ikeda,Tsuneko; Imai,Atsushi

doi:10.3892/ol.2011.453

Transitional cell carcinoma of the ovary (Review)

Authors:
- Satoshi Ichigo
- Hiroshi Takagi
- Kazutoshi Matsunami
- Takayuki Murase
- Tsuneko Ikeda
- Atsushi Imai
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Affiliations: Department of Obstetrics and Gynecology, Matsunami General Hospital, Gifu 501-6062, Japan, Department of Pathology, Matsunami General Hospital, Gifu 501-6062, Japan
Published online on: October 21, 2011 https://doi.org/10.3892/ol.2011.453
Pages: 3-6

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Abstract

Transitional cell carcinoma (TCC) of the ovary is a rare recently recognized subtype of ovarian epithelial cancer. Ovarian TCC has a modest response to chemotherapy, and metastatic TCC from the renal pelvis results in mortality. The clinical presentation is indistinguishable from other types of ovarian carcinoma. Histopathological examination remains the first tool used in the diagnosis of these heterogeneous tumors and in the separation of closely related tumors. Since it is generally accepted that surgical resection is the primary therapeutic approach, and patient outcomes following chemotherapy are better than for other types of ovarian cancers, it is a reasonable concept to detect tumors when they are still confined within the ovaries. Thus, the aim of this review was to describe typical cases of primary TCC, and to review the medical literature for information on TCC management in order to determine appropriate diagnostic methods and therapy.

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