Assessment of the feeding arteries by three-dimensional computed tomography angiography prior to multi‑arterial infusion chemotherapy for lung cancer

Ye,Xiao-Dan; Yuan,Zheng; Ye,Jian-Ding; Xiao,Xiang-Sheng

doi:10.3892/ol.2012.1000

Assessment of the feeding arteries by three-dimensional computed tomography angiography prior to multi‑arterial infusion chemotherapy for lung cancer

Authors:
- Xiao-Dan Ye
- Zheng Yuan
- Jian-Ding Ye
- Xiang-Sheng Xiao
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Affiliations: Department of Radiology, Shanghai Chest Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200030, P.R. China, Department of Radiology, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China, Department of Radiology Affiliated to Changzheng Hospital, The Second Military Medical University, Shanghai 200003, P.R. China
Published online on: October 26, 2012 https://doi.org/10.3892/ol.2012.1000
Pages: 363-367

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Abstract

The aim of this study was to evaluate the efficacy of multi-detector row helical computed tomography (MDCT) angiography in the detection of feeding arteries prior to multi‑arterial infusion for lung cancer. A total of 59 consecutive patients (44 males and 15 females; age range, 27-86 years; median age, 62 years) with non-small cell lung cancer underwent MDCT angiography of the thorax prior to multi‑arterial infusion for lung cancer. Findings on CT angiograms, including CT scans, maximum intensity projections and three‑dimensional volume-rendered images, were used to evaluate the depiction of bronchial and non-bronchial systemic arteries. The results of detecting the feeding arteries for lung cancer by MDCT angiography and conventional angiography were compared. Among the 59 patients treated with multi‑arterial infusion chemotherapy, a total of 80 feeding arteries (62 bronchial feeding arteries and 18 non-bronchial systemic arteries) were detected by conventional angiography and/or MDCT angiography. In 56 (70%) feeding arteries (including 44 bronchial feeding arteries and 12 non‑bronchial systemic arteries) for lung cancers, concordant findings were observed with the two modalities. In 23 (29%) cases, MDCT angiography could not be used to define feeding arteries, but was used to identify the ostia of these feeding arteries. In one (1/80, 1.3%) case, the CT-defined feeding artery was not selectively catheterized. MDCT angiography of the chest is able to provide an overview for successful catheterization in multi‑arterial infusion chemotherapy for lung cancer.

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1	Jemal A, Bray F, Center MM, Ferlay J, Ward E and Forman D: Global cancer statistics. CA Cancer J Clin. 61:69–90. 2011. View Article : Google Scholar
2	Viamonte M Jr: Selective bronchial arteriography in man; preliminary report. Radiology. 83:830–839. 1964. View Article : Google Scholar : PubMed/NCBI
3	Neyazaki T, Ikeda M, Seki Y, Egawa N and Suzuki C: Bronchial artery infusion therapy for lung cancer. Cancer. 24:912–922. 1969. View Article : Google Scholar : PubMed/NCBI
4	Yiengpruksawa A, Watanabe G, Ono Y, Tsurumaru M and Akiyama H: Tracheoesophageal fistula as a result of bronchial artery infusion therapy. Int Surg. 69:351–355. 1984.
5	Munk PL, Morris DC and Nelems B: Left main bronchial-esophageal fistula: a complication of bronchial artery embolization. Cardiovasc Intervent Radiol. 13:95–97. 1990. View Article : Google Scholar : PubMed/NCBI
6	Hellekant C and Jonsson K: Double blood supply of bronchial carcinoma from multiple arteries. Acta Radiol Diagn (Stockholm). 22:403–406. 1981.PubMed/NCBI
7	Nakanishi M, Umeda Y, Demura Y, Ameshima S, Chiba Y, Miyamori I and Ishizaki T: Effective use of multi-arterial infusion chemotherapy for advanced non-small cell lung cancer patients: four clinical specified cases. Lung Cancer. 55:241–247. 2007. View Article : Google Scholar : PubMed/NCBI
8	Nakanishi M, Demura Y, Umeda Y, Mizuno S, Ameshima S, Chiba Y and Ishizaki T: Multi-arterial infusion chemotherapy for non-small cell lung carcinoma-significance of detecting feeding arteries and tumor staining. Lung Cancer. 61:227–234. 2008. View Article : Google Scholar : PubMed/NCBI
9	Watanabe S, Arai K, Watanabe T, Koda W and Urayama H: Use of three-dimensional computed tomographic angiography of pulmonary vessels for lung resections. Ann Thorac Surg. 75:388–392. 2003. View Article : Google Scholar : PubMed/NCBI
10	Fukuhara K, Akashi A, Nakane S and Tomita E: Preoperative assessment of the pulmonary artery by three-dimensional computed tomography before video-assisted thoracic surgery lobectomy. Eur J Cardiothorac Surg. 34:875–877. 2008. View Article : Google Scholar
11	Nakamoto K, Omori K and Nezu K; Lung Cancer Project Group of West-Seto Inland Sea, Japan: Superselective segmentectomy for deep and small pulmonary nodules under the guidance of three-dimensional reconstructed computed tomographic angiography. Ann Thorac Surg. 89:877–883. 2010. View Article : Google Scholar
12	Yu H, Liu SY, Li HM, Xiao XS and Dong WH: Empirical description of bronchial and nonbronchial arteries with MDCT. Eur J Radiol. 75:147–53. 2010. View Article : Google Scholar : PubMed/NCBI
13	Murayama S, Hashiguchi N, Murakami J, Sakai S, Matsumoto S, Mizushima A, Hasuo K and Masuda K: Helical CT imaging of bronchial arteries with curved reformation technique in comparison with selective bronchial arteriography: preliminary report. J Comput Assist Tomogr. 20:749–755. 1996. View Article : Google Scholar
14	Remy-Jardin M, Bouaziz N, Dumont P, Brillet PY, Bruzzi J and Remy J: Bronchial and nonbronchial systemic arteries at multi-detector row CT angiography: comparison with conventional angiography. Radiology. 233:741–749. 2004. View Article : Google Scholar : PubMed/NCBI
15	Hartmann IJ, Remy-Jardin M, Menchini L, Teisseire A, Khalil C and Remy J: Ectopic origin of bronchial arteries: assessment with multidetector helical CT angiography. Eur Radiol. 17:1943–1953. 2007. View Article : Google Scholar : PubMed/NCBI
16	Remy J and Remy-Jardin M: Bronchial bleeding. International Radiology. Dondelinger RF, Rossi P, Kurdziel JC and Wallace S: Thieme; Stuttgart, Germany: pp. 325–341. 1990
17	Yoon W, Kim JK, Kim YH, Chung TW and Kang HK: Bronchial and nonbronchial systemic artery embolization for life-threatening hemoptysis: a comprehensive review. Radiographics. 22:1395–1409. 2002. View Article : Google Scholar : PubMed/NCBI
18	Osaki T, Hanagiri T, Nakanishi R, Yoshino I, Taga S and Yasumoto K: Bronchial arterial infusion is an effective therapeutic modality for centrally located early-stage lung cancer. results of a pilot study. Chest. 115:1424–1428. 1999. View Article : Google Scholar : PubMed/NCBI
19	Watanabe Y, Shimizu J, Murakami S, Yoshida M, Tsubota M, Iwa T, Kitagawa M, Mizukami Y, Nonomura A and Matsubara F: Reappraisal of bronchial arterial infusion therapy for advanced lung cancer. Jpn J Surg. 20:27–35. 1990. View Article : Google Scholar : PubMed/NCBI
20	Littleton JT, Durizch ML, Moeller G and Herbert DE: Pulmonary masses: contrast enhancement. Radiology. 177:861–871. 1990. View Article : Google Scholar : PubMed/NCBI
21	Jeong YJ, Lee KS, Jeong SY, Chung MJ, Shim SS, Kim H, Kwon OJ and Kim S: Solitary pulmonary nodule: characterization with combined wash-in and washout features at dynamic multidetector row CT. Radiology. 237:675–683. 2005. View Article : Google Scholar : PubMed/NCBI