Pathological and computed tomography findings of lymphoepithelioma‑like gastric carcinoma with epithelioid granulomas: A case report

Liu,Shuguang; Jin,Long; Xu,Xiaoyan; Lin,Ni; Lei,Bin; Shen,Hong

doi:10.3892/ol.2012.1070

Pathological and computed tomography findings of lymphoepithelioma‑like gastric carcinoma with epithelioid granulomas: A case report

Authors:
- Shuguang Liu
- Long Jin
- Xiaoyan Xu
- Ni Lin
- Bin Lei
- Hong Shen
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Affiliations: Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P.R. China, Department of Pathology, Fujian Provincial Hospital, Fuzhou, P.R. China, Department of Pathology, People's Hospital of Zhengzhou Attached to Southern Medical University, Zhengzhou, P.R. China , Huiqiao Department, Nanfang Hospital, Southern Medical University, Guangzhou, P.R. China
Published online on: December 12, 2012 https://doi.org/10.3892/ol.2012.1070
Pages: 549-551

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Abstract

Lymphoepithelioma‑like carcinoma is a distinct entity among Epstein‑Barr virus (EBV)‑associated gastric carcinomas, characterized by the presence of a lymphoid stroma with small nests of cancer cells uniformly distributed throughout. Epithelioid granulomas with multinucleated giant cells are extremely rare in the tumor tissue. The presence of epithelioid granulomas with prominent lymphocyte infiltration is associated with a favorable prognosis. This lesion tends to form a bulging mass in the submucosa. In the present study, we report a lymphoepithelioma‑like carcinoma of the stomach with epithelioid granulomas which appeared as a bulging mass in CT scanning and correlate it with the pathology. Clinicians and radiologists should recognize the features of such tumors.

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