Primary testicular non-Hodgkin's lymphoma associated with hemophagocytic syndrome: Case report and review of the literature

Ren,Weigang; Zhong,Zhaohui; Zhao,Xiaokun; Yang,Junjie; Zhang,Lei; Xu,Ran; Li,Songchao; Zhu,Xuan; Lu,Chen; Chin,Joseph  L.

doi:10.3892/ol.2012.701

Primary testicular non-Hodgkin's lymphoma associated with hemophagocytic syndrome: Case report and review of the literature

Authors:
- Weigang Ren
- Zhaohui Zhong
- Xiaokun Zhao
- Junjie Yang
- Lei Zhang
- Ran Xu
- Songchao Li
- Xuan Zhu
- Chen Lu
- Joseph L. Chin
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Affiliations: Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China, Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China, Department of Hematology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China, Department of Urology, Shanghai Changhai Hospital, Shanghai 200433, P.R. China, Department of Urology and Oncology, University of Western Ontario, London, Ontario N6A 4V2, Canada
Published online on: April 30, 2012 https://doi.org/10.3892/ol.2012.701
Pages: 59-62

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Abstract

Primary testicular non-Hodgkin's lymphoma (TNHL) was first described as a clinical entity in 1866. It is a rare disease which accounts for 1% of all non-Hodgkin's lymphoma, 2% of all extranodal lymphomas and 5% of all testicular neoplasms. Hemophagocytic syndrome (HPS) is a rare but distinct condition caused by inappropriate and dysregulated activation of the immune system. We report a 47-year-old man with primary TNHL who developed HPS four months after occurrence of scrotal swelling. To the best of our knowledge, primary TNHL associated with HPS has not previously been reported.

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