Aggressive angiomyxoma of the thigh: A case report and review of the literature

Liu,Xinying; Li,Xinghua; Yang,Yinlong

doi:10.3892/ol.2012.743

Aggressive angiomyxoma of the thigh: A case report and review of the literature

Authors:
- Xinying Liu
- Xinghua Li
- Yinlong Yang
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Affiliations: Department of Ultrasound, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou, Zhejiang 325000, P.R. China, Department of Urinary Surgery, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou, Zhejiang 325000, P.R. China, Department of Surgical Oncology, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou, Zhejiang 325000, P.R. China
Published online on: June 7, 2012 https://doi.org/10.3892/ol.2012.743
Pages: 467-470

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Abstract

In this study, we report a case of aggressive angiomyxoma (AAM) of the thigh in a 43-year-old female patient. Ultrasonography revealed a 6.1x3.7x5.3 cm solid mass in the right thigh with well-demarcated borders and a heterogeneous echotexture. Color Doppler ultrasonography (CDUS) revealed weak blood flow in the mass with peripheral and central avascularity. Computed tomography (CT) of the thigh revealed a homogeneous low-density mass under the spatium intermusculare of the quadriceps femoris. The mass was diagnosed as AAM by histopathological examination following complete excision around the adventitia of the tumor. At 18 months follow-up, there was no recurrence. In conclusion, this case is noteworthy as it involves AAM of the thigh, which is a rare tumor.

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1	Steeper TA and Rosai J: Aggressive angiomyxoma of the female pelvis and perineum. Report of nine cases of a distinctive type of gynaecologic soft-tissue neoplasm. Am J Surg Pathol. 7:463–475. 1983. View Article : Google Scholar : PubMed/NCBI
2	Sylvester DC, Kortequee S, Moor JW, et al: Aggressive angiomyxoma of larynx: case report and literature review. J Laryngol Otol. 124:793–795. 2010. View Article : Google Scholar : PubMed/NCBI
3	Idrees MT, Hoch BL, Wang BY and Unger PD: Aggressive angiomyxoma of the male genital region. Report of 4 cases with immunohistochemical evaluation including hormone receptor status. Ann Diagn Pathol. 10:197–204. 2006. View Article : Google Scholar
4	Pai CY, Nieh S, Lee JC, et al: Aggressive angiomyxoma of supraclavicular fossa: a case report. Head Neck. 30:821–824. 2008. View Article : Google Scholar : PubMed/NCBI
5	Heffernan EJ, Hayes MM, Alkubaidan FO, et al: Aggressive angiomyxoma of the thigh: case report. Skeletal Radiol. 37:673–678. 2008. View Article : Google Scholar
6	Fine BA, Munoz AK, Litz CE, et al: Primary medical management of recurrent aggressive angiomyxoma of the vulva with a gonadotropin-releasing hormone agonist. Gynecol Oncol. 81:120–122. 2001. View Article : Google Scholar : PubMed/NCBI
7	Chihara Y, Fujimoto K, Takada S, et al: Aggressive angiomyxoma in the scrotum expressing androgen and progesterone receptors. Int J Urol. 10:672–675. 2003. View Article : Google Scholar : PubMed/NCBI
8	Dahiya K, Jain S, Duhan N, et al: Aggressive angiomyxoma of vulva and vagina: a series of three cases and review of literature. Arch Gynecol Obstet. 283:1145–1148. 2011. View Article : Google Scholar : PubMed/NCBI
9	Chan YM, Hon E, Ngai SW, et al: Aggressive angiomyxoma in females: is radical resection the only option? Acta Obstet Gynecol Scand. 79:216–220. 2000. View Article : Google Scholar : PubMed/NCBI
10	Nyan DCK and Pemberton J: Large aggressive angiomyxoma of the perineum and perineum and pelvis: an alternative approach. Diseases of the Colon and Rectum. 41:514–516. 1998. View Article : Google Scholar
11	Jingping Z and Chunfu Z: Clinical experiences on aggressive angiomyxoma in China (report of 93 cases). Int J Gynecol Cancer. 20:303–307. 2010. View Article : Google Scholar : PubMed/NCBI
12	Hatano K, Tsujimoto Y, Ichimaru A, et al: Rare case of aggressive angiomyxoma presenting as a retrovesical tumor. Int J Urol. 13:1012–1014. 2006. View Article : Google Scholar : PubMed/NCBI
13	Nucci MR and Fletcher CD: Vulvovaginal soft tissue tumors: update and review. Histopathology. 36:97–108. 2000. View Article : Google Scholar : PubMed/NCBI
14	Wiser A, Korach J, Gotlieb W, et al: Importance of accurate preoperative diagnosis in the management of aggressive angiomyxoma: report of three cases and review of the literature. Abdom Imaging. 31:383–386. 2006. View Article : Google Scholar : PubMed/NCBI
15	Fetsch JF, Laskin WB, Lefkowitz M, et al: Aggressive angiomyxoma: a clinicopathological study of 29 female patients. Cancer. 78:79–90. 1996. View Article : Google Scholar
16	Begin LR, Clement PB, Kirk ME, et al: Aggressive angiomyxoma of pelvis soft parts: a clinicopathologic study of nine cases. Hum Pathol. 16:621–628. 1985. View Article : Google Scholar : PubMed/NCBI