1.
|
A JemalR SiegelE WardCancer statistics,
2006CA Cancer J Clin56106130200610.3322/canjclin.56.2.106
|
2.
|
AN ShahJM SummyJ ZhangSI ParkNU ParikhGE
GallickDevelopment and characterization of gemcitabine-resistant
pancreatic tumor cellsAnn Surg
Oncol1436293637200710.1245/s10434-007-9583-517909916
|
3.
|
A JemalT MurrayA SamuelsA GhafoorE WardMJ
ThunCancer statistics, 2003CA Cancer J
Clin53526200310.3322/canjclin.53.1.5
|
4.
|
TS RiallWH NealonJS GoodwinPancreatic
cancer in the general population: Improvements in survival over the
last decadeJ Gastrointest Surg1012121223discussion 1223–1214,
2006.
|
5.
|
HL PearceM Alice MillerThe evolution of
cancer research and drug discovery at Lilly Research
LaboratoriesAdv Enzyme
Regul45229255200510.1016/j.advenzreg.2005.02.01716143373
|
6.
|
Y ShenM CaiW XiaFTY720, a synthetic
compound from Isaria sinclairii, inhibits proliferation and induces
apoptosis in pancreatic cancer cellsCancer
Lett254288297200710.1016/j.canlet.2007.03.01317462818
|
7.
|
SH LeeJK RyuKY LeeEnhanced anti-tumor
effect of combination therapy with gemcitabine and apigenin in
pancreatic cancerCancer
Lett2593949200810.1016/j.canlet.2007.09.01517967505
|
8.
|
HA Burris IIIMJ MooreJ
AndersenImprovements in survival and clinical benefit with
gemcitabine as first-line therapy for patients with advanced
pancreas cancer: a randomized trialJ Clin
Oncol152403241319979196156
|
9.
|
K KimuraT SawadaM KomatsuAntitumor effect
of trastuzumab for pancreatic cancer with high HER-2 expression and
enhancement of effect by combined therapy with gemcitabineClin
Cancer Res1249254932200610.1158/1078-0432.CCR-06-054416914581
|
10.
|
M WatabeN KawazoeY MasudaS NakajoK
NakayaBcl-2 protein inhibits bufalin-induced apoptosis through
inhibition of mitogen-activated protein kinase activation in human
leukemia U937 cellsCancer Res57309731001997
|
11.
|
N TakaiT UedaM NishidaK NasuH
NaraharaBufalin induces growth inhibition, cell cycle arrest and
apoptosis in human endometrial and ovarian cancer cellsInt J Mol
Med21637643200818425357
|
12.
|
CH YuSF KanHF PuE Jea ChienPS
WangApoptotic signaling in bufalin- and cinobufagin-treated
androgen-dependent and -independent human prostate cancer
cellsCancer
Sci9924672476200810.1111/j.1349-7006.2008.00966.x19037992
|
13.
|
K NasuM NishidaT UedaBufalin induces
apoptosis and the G0/G1 cell cycle arrest of endometriotic stromal
cells: a promising agent for the treatment of endometriosisMol Hum
Reprod11817823200510.1093/molehr/gah24916390854
|
14.
|
CT KuoBC ChenCC YuApoptosis
signal-regulating kinase 1 mediates denbinobin-induced apoptosis in
human lung adenocarcinoma cellsJ Biomed
Sci1643200910.1186/1423-0127-16-4319405983
|
15.
|
W SchonerG Scheiner-BobisEndogenous and
exogenous cardiac glycosides: their roles in hypertension, salt
metabolism, and cell growthAm J Physiol Cell
Physiol293C509536200710.1152/ajpcell.00098.200717494630
|
16.
|
Y AmanoY ChoM MatsunawaK KomiyamaM
MakishimaIncreased nuclear expression and transactivation of
vitamin D receptor by the cardiotonic steroid bufalin in human
myeloid leukemia cellsJ Steroid Biochem Mol
Biol114144151200910.1016/j.jsbmb.2009.01.022
|
17.
|
ZY TangYL WuSL GaoHW ShenEffects of the
proteasome inhibitor bortezomib on gene expression profiles of
pancreatic cancer cellsJ Surg
Res145111123200810.1016/j.jss.2007.03.06117714734
|
18.
|
Q GuoY ChenB ZhangM KangQ XieY
WuPotentiation of the effect of gemcitabine by emodin in pancreatic
cancer is associated with survivin inhibitionBiochem
Pharmacol7716741683200910.1016/j.bcp.2009.02.02119428321
|
19.
|
M KornmannHG BegerKH LinkChemosensitivity
testing and test-directed chemotherapy in human pancreatic
cancerRecent Results Cancer
Res161180195200310.1007/978-3-642-19022-3_1512528808
|
20.
|
A ZalatnaiJ MolnarReview. Molecular
background of chemoresistance in pancreatic cancerIn
Vivo21339347200717436586
|
21.
|
M MimeaultR HaukeSK BatraRecent advances
on the molecular mechanisms involved in the drug resistance of
cancer cells and novel targeting therapiesClin Pharmacol
Ther83673691200810.1038/sj.clpt.610029617786164
|
22.
|
L SunT ChenX WangY ChenX WeiBufalin
induces reactive oxygen species dependent bax translocation and
apoptosis in ASTC-a-1 cellsEvid Based Complement Alternat
Med200919592481
|
23.
|
CM XieWY ChanS YuJ ZhaoCH ChengBufalin
induces autophagy-mediated cell death in human colon cancer cells
through reactive oxygen species generation and JNK activationFree
Radic Biol Med5113651375201110.1016/j.freeradbiomed.2011.06.016
|
24.
|
K OkamotoM OckerD Neureiterbcl-2-specific
siRNAs restore gemcitabine sensitivity in human pancreatic cancer
cellsJ Cell Mol
Med11349361200710.1111/j.1582-4934.2007.00013.x17378914
|
25.
|
M KurosawaS NumazawaY TaniT YoshidaERK
signaling mediates the induction of inflammatory cytokines by
bufalin in human monocytic cellsAm J Physiol Cell
Physiol278C500508200010712238
|
26.
|
N KawazoeM WatabeY MasudaS NakajoK
NakayaTiam1 is involved in the regulation of bufalin-induced
apoptosis in human leukemia
cellsOncogene1824132421199910.1038/sj.onc.120255510229192
|
27.
|
M KurosawaY TaniS NishimuraS NumazawaT
YoshidaDistinct PKC isozymes regulate bufalin-induced
differentiation and apoptosis in human monocytic cellsAm J Physiol
Cell Physiol280C459C464200111171564
|
28.
|
T HataiA MatsuzawaS InoshitaExecution of
apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by
the mitochondria-dependent caspase activationJ Biol
Chem2752657626581200010.1074/jbc.M00341220010849426
|
29.
|
H IchijoE NishidaK IrieInduction of
apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and
p38 signaling
pathwaysScience2759094199710.1126/science.275.5296.908974401
|
30.
|
S NumazawaMA ShinokiH ItoT YoshidaY
KuroiwaInvolvement of Na+,K(+)-ATPase inhibition in K562 cell
differentiation induced by bufalinJ Cell Physiol1601131201994
|
31.
|
Y JingM WatabeS HashimotoS NakajoK
NakayaCell cycle arrest and protein kinase modulating effect of
bufalin on human leukemia ML1 cellsAnticancer
Res141193119819948074471
|
32.
|
Y MasudaN KawazoeS NakajoT YoshidaY
KuroiwaK NakayaBufalin induces apoptosis and influences the
expression of apoptosis-related genes in human leukemia cellsLeuk
Res19549556199510.1016/0145-2126(95)00031-I7658701
|
33.
|
F SuH LiC YanB JiaY ZhangX ChenDepleting
MEKK1 expression inhibits the ability of invasion and migration of
human pancreatic cancer cellsJ Cancer Res Clin
Oncol13516551663200910.1007/s00432-009-0612-619513748
|
34.
|
CC YuMJ HsuML KuoThrombin-induced
connective tissue growth factor expression in human lung
fibroblasts requires the ASK1/JNK/AP-1 pathwayJ
Immunol18279167927200910.4049/jimmunol.080158219494316
|
35.
|
K YamamotoH IchijoSJ KorsmeyerBCL-2 is
phosphorylated and inactivated by an ASK1/Jun N-terminal protein
kinase pathway normally activated at G(2)/MMol Cell
Biol1984698478199910567572
|