Primary giant lymphoma of the right thigh: A case report and brief review of the literature

Gao,Yu-Huan; Xu,Qian; Wei,Guangchuan; Liu,Hai-Sheng; Wu,Xiaolin; Liu,Li-Hong; Wu,Li-Li; Zhao,Gui-Min; Diao,Lan-Ping

doi:10.3892/ol.2012.848

Primary giant lymphoma of the right thigh: A case report and brief review of the literature

Authors:
- Yu-Huan Gao
- Qian Xu
- Guangchuan Wei
- Hai-Sheng Liu
- Xiaolin Wu
- Li-Hong Liu
- Li-Li Wu
- Gui-Min Zhao
- Lan-Ping Diao
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Affiliations: Department of Hematology, Hebei Medical University, Fourth Hospital, Shijiazhuang, Hebei 050011, P.R. China, Department of Radiology, Hebei Medical University, Fourth Hospital, Shijiazhuang, Hebei 050011, P.R. China, Department of Ophthalmology, Hebei Medical University, Fourth Hospital, Shijiazhuang, Hebei 050011, P.R. China
Published online on: August 6, 2012 https://doi.org/10.3892/ol.2012.848
Pages: 1023-1026

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Abstract

Primary soft tissue non-Hodgkin lymphoma (NHL) of the extremities is very rare. The clinical features of NHL mimic those of other soft tissue tumors, particularly sarcoma; however, they should be differentiated, as the treatment and prognosis are completely different. In this study, the case of a 68-year-old female with a giant mass, movement disorder, numbness and painful sensations in the right thigh is presented. Magnetic resonance (MR) imaging revealed a huge circle-shaped mass. Fine needle aspiration cytology (FNAC) of the tumor demonstrated neoplastic small, round cells. The tentative diagnosis was of a mesenchymal sarcoma. The right thigh was amputated. On histological examination of the amputated extremity, the diagnosis was found to be large B cell lymphoma. Primary soft tissue NHL of the extremities is a systemic malignant disease and is sensitive to chemotherapy and radiotherapy. The histological diagnosis should be identified as far as possible before the tumor is widely excised.

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