Isolated solitary brain metastasis as a relapse of small cell lung cancer

Sakurai,Hirofumi; Kurishima,Koichi; Homma,Shinsuke; Kagohashi,Katsunori; Miyazaki,Kunihiko; Kawaguchi,Mio; Satoh,Hiroaki; Hizawa,Nobuyuki

doi:10.3892/ol.2013.1489

Isolated solitary brain metastasis as a relapse of small cell lung cancer

Authors:
- Hirofumi Sakurai
- Koichi Kurishima
- Shinsuke Homma
- Katsunori Kagohashi
- Kunihiko Miyazaki
- Mio Kawaguchi
- Hiroaki Satoh
- Nobuyuki Hizawa
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Affiliations: Division of Respiratory Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan, Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015, Japan
Published online on: July 24, 2013 https://doi.org/10.3892/ol.2013.1489
Pages: 1108-1110

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Abstract

The brain is one of the most common sites for the metastasis of small cell lung cancer (SCLC). The present study describes two cases of an isolated solitary brain metastasis as a relapse of SCLC, which occurred more than one year after the completion of the initial successful treatment for SCLC. The tumors were identified during a regular check‑up computed tomography (CT) scan and were successfully treated. To the best of our knowledge, this is the first study to report the cases of two patients with an isolated solitary brain metastasis as a relapse of SCLC. Although extremely rare, the possibility of such recurrences should be considered, particularly in patients who have refused prophylactic cranial irradiation.

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