A rare case of primary nodal hemangioendothelioma

Donato,Giuseppe; Conforti,Francesco; Allegra,Eugenia

doi:10.3892/ol.2013.1631

December 2013 Volume 6 Issue 6

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December 2013 Volume 6 Issue 6

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Article

A rare case of primary nodal hemangioendothelioma

Authors:
- Giuseppe Donato
- Francesco Conforti
- Eugenia Allegra
View Affiliations / Copyright

Affiliations: Department of Pathology, School of Medicine, University Magna Graecia, Campus of Germaneto, Catanzaro I‑88100, Italy, Department of Otolaryngology, School of Medicine, University Magna Graecia, Campus of Germaneto, Catanzaro I‑88100, Italy
Pages: 1759-1761
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Published online on: October 15, 2013

https://doi.org/10.3892/ol.2013.1631
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Abstract

Primary vascular tumors of the lymph nodes other than Kaposi's sarcoma are rare. The present study describes the case of a primary hemangioendothelioma in a cervical lymph node in a patient treated for a carcinoma of the large bowel. Microscopically, the structure of the lymph node was completely substituted by tumoral proliferation, with an architectural pattern consisting of anastomosing vascular channels, a number of which contained papillary projections or a tuft-like structure. This study demonstrates the potential diagnostic errors and hypothesizes the pathogenesis of this type of lesion; a vascular endothelial growth factor (VEGF)/VEGF receptor‑3 (VEGFR‑3) autocrine loop may be activated.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

A rare case of primary nodal hemangioendothelioma

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Abstract

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