Granulocytic sarcoma of the breast in acute myeloid leukemia: Two case reports
- Authors:
View Affiliations
Affiliations: Department of Oncology, Jinhua Central Hospital, Jinhua, Zhejiang 321000, P.R. China
- Published online on: November 19, 2013 https://doi.org/10.3892/ol.2013.1687
-
Pages:
145-147
Metrics: Total
Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
This article is mentioned in:
Abstract
Granulocytic sarcoma (GS) of the breast is extremely rare in patients with acute myeloid leukemia (AML) and therefore, is often misdiagnosed as lymphoma or other benign tumors. The current report presents two cases of GS of the breast, of which, one was considered to be a fibroma, as observed by fine‑needle aspiration, and the other was misdiagnosed as lymphoma by frozen section. Previous literature that described the clinical and pathological characteristics, treatments and prognosis of GS of the breast in AML were reviewed. In addition to the treatment of mastectomy with/without radiotherapy, lumpectomy may also be received as a good treatment plan.
View References
|
1
|
Liu PI, Ishimaru T, McGregor DH, Okada H
and Steer A: Autopsy study of granulocytic sarcoma (chloroma) in
patients with myelogenous leukemia, Hiroshima-Nagasaki 1949–1969.
Cancer. 31:948–955. 1973.PubMed/NCBI
|
|
2
|
Byrd JC, Edenfield WJ, Shields DJ and
Dawson NA: Extramedullary myeloid cell tumors in acute
nonlymphocytic leukemia: a clinical review. J Clin Oncol.
13:1800–1816. 1995.PubMed/NCBI
|
|
3
|
Firas AS, Demeckova E, Bojtarova E, Czako
B, Hrubisko M and Mistrik M: Isolated extra-medullary relapse of
acute leukemia following allogeneic bone marrow transplantation.
Bratisl Lek Listy. 109:358–361. 2008.
|
|
4
|
Karbasian-Esfahani M, Wiernik PH, Yeddu M
and Abebe L: Leukemic infiltration of the breast in acute
lymphocytic leukemia (ALL). Hematology. 13:101–106. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Koca E, Goker H, Guven GS, et al: Unusual
extramedullary recurrences and breast relapse despite hepatic GVHD
after allografting in Ph+-ALL. Hematology. 11:105–107.
2006.PubMed/NCBI
|
|
6
|
Thachil J, Richards RM and Copeland G:
Granulocytic sarcoma - a rare presentation of a breast lump. Ann R
Coll Surg Engl. 89:W7–W9. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Yang WT, Muttarak M and Ho LW: Nonmammary
malignancies of the breast: ultrasound, CT, and MRI. Semin
Ultrasound CT MR. 21:375–394. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Khoury NJ, Hanna Al-Kass FM, Jaafar HN,
Taher AT and Shamseddine AI: Bilateral breast involvement in acute
myelogenous leukemia. Eur Radiol. 10:10312000. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Shea B, Reddy V, Abbitt P, Benda R,
Douglas V and Wingard J: Granulocytic sarcoma (chloroma) of the
breast: a diagnostic dilemma and review of the literature. Breast
J. 10:48–53. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Pettinato G, De Chiara A, Insabato L and
De Renzo A: Fine needle aspiration biopsy of a granulocytic sarcoma
(chloroma) of the breast. Acta Cytol. 32:67–71. 1988.PubMed/NCBI
|
|
11
|
Traweek ST, Arber DA, Rappaport H and
Brynes RK: Extramedullary myeloid cell tumors. An
immunohistochemical and morphologic study of 28 cases. Am J Surg
Pathol. 17:1011–1019. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Mandal S, Jain S and Khurana N: Breast
lump as an initial manifestation in acute lymphoblastic leukemia:
an unusual presentation. A case report. Hematology. 12:45–47. 2007.
View Article : Google Scholar
|
