Angiomyofibroblastoma‑like tumor of the scrotum: A case report and literature review

Ding,Guoqing; Yu,Yanlan; Jin,Mei; Xu,Jingyao; Zhang,Zhigen

doi:10.3892/ol.2013.1741

Angiomyofibroblastoma‑like tumor of the scrotum: A case report and literature review

Authors:
- Guoqing Ding
- Yanlan Yu
- Mei Jin
- Jingyao Xu
- Zhigen Zhang
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Affiliations: Department of Urology, Sir Run‑Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China
Published online on: December 6, 2013 https://doi.org/10.3892/ol.2013.1741
Pages: 435-438

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Abstract

The purpose of the present study was to increase the knowledge of angiomyofibroblastoma (AMF)‑like tumors in males by describing the second case of this rare lesion in the Chinese population with a long period of follow‑up and by reviewing the literature. AMF‑like tumor is a rare, circumscribed, slow‑growing mesenchymal tumor that occurs predominantly in the vulva, perineum and pelvis of females. The present report presents a case of left scrotal AMF‑like tumor in a 37‑year‑old male. Complete surgical excision was performed. The tumor was composed of spindle‑shaped cells and small vessels proliferating in the edematous stroma. Immunohistologically, the tumor cells stained positive for smooth muscle actin and negative for S‑100, CD34 and actin. Following seven years of follow‑up the patient was asymptomatic and no evidence of tumor was found. In addition, the current literature was reviewed and the characteristics of this tumor were summarized. AMF‑like tumors must also be distinguished from spindle cell lipoma, solitary fibrous tumor and aggressive angiomyxoma.

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