Late‑onset sarcoidosis in a patient with gastric mucosa‑associated lymphoid tissue non‑Hodgkin lymphoma: A case report

Torchio,Martina; Bottaro,Giorgio; Bertolino,Giampiera; Comolli,Giuditta; Dal Bello,Barbara; Invernizzi,Rosangela; Danova,Marco

doi:10.3892/ol.2014.2241

Late‑onset sarcoidosis in a patient with gastric mucosa‑associated lymphoid tissue non‑Hodgkin lymphoma: A case report

Authors:
- Martina Torchio
- Giorgio Bottaro
- Giampiera Bertolino
- Giuditta Comolli
- Barbara Dal Bello
- Rosangela Invernizzi
- Marco Danova
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Affiliations: Department of Internal Medicine and Medical Oncology, Civic Hospital of Vigevano, Pavia I‑27029, Italy, Department of Internal Medicine, IRCCS Foundation Policlinico San Matteo, University of Pavia, Pavia I-27100, Italy, Department of Biotechnology Research Laboratory and Microbiology and Virology, IRCCS Foundation Policlinico San Matteo, University of Pavia, Pavia I-27100, Italy, Department of Pathology, University of Pavia, Pavia I-27100, Italy
Published online on: June 12, 2014 https://doi.org/10.3892/ol.2014.2241
Pages: 1299-1301

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Abstract

The simultaneous presence of hematological malignancies and sarcoidosis, defined as sarcoidosis‑lymphoma syndrome, has been reported in 79 patients in the literature to date. The majority of these patients were affected by sarcoidosis and developed non‑Hodgkin lymphoma or acute leukemia after 1‑2 years; however, in <20 cases the malignancy developed first. This report presents the case of an 83‑year‑old male with a clinical history of Helicobacter pylori‑positive gastric mucosa‑associated lymphoid tissue lymphoma. The patient developed sarcoidosis 10 years after the first diagnosis, which caused the diagnostic work‑up and differential diagnosis between a lymphoma relapse and de novo sarcoidosis to be challenging.

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