Long‑term survival of a patient with scalp angiosarcoma and multiple metastases treated using combination therapy: A case report

Ye,Jun; Li,Xiao‑Fen; Wang,Yong‑Dong; Yuan,Ying

doi:10.3892/ol.2015.2919

Long‑term survival of a patient with scalp angiosarcoma and multiple metastases treated using combination therapy: A case report

Authors:
- Jun Ye
- Xiao‑Fen Li
- Yong‑Dong Wang
- Ying Yuan
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Affiliations: Department of Dermatology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. China, Department of Medical Oncology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. China
Published online on: January 29, 2015 https://doi.org/10.3892/ol.2015.2919
Pages: 1725-1728

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Abstract

Angiosarcoma is a rare and deadly malignancy originating from the vascular endothelial cells. Surgery is the most effective method to cure this disease, but for metastatic angiosarcoma, a chemotherapy‑based treatment is the main therapeutic choice. However, there is currently no standard chemotherapy regimen. The current study reports the case of a 66‑year‑old male with post‑operative scalp angiosarcoma recurrence and multiple metastases. The patient obtained a complete response to first‑line combination chemotherapy consisting of cyclophosphamide, epirubicin, vincristine and dacarbazine, with a progression‑free survival time of eight months. After benefitting from subsequent comprehensive treatment including, cyclophosphamide, epirubicin, vincristine, dacarbazine, docetaxel, cisplatin, gemcitabine and radiotherapy and anti‑angiogenic therapy, the patient obtained an overall survival time of 38 months following initial diagnosis.

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