Extramedullary plasmacytoma of the cricoid cartilage progressing to multiple myeloma: A case report
- Authors:
- Min Wang
- Jintao Du
- Jian Zou
- Shixi Liu
View Affiliations
Affiliations: Department of Otorhinolaryngology‑Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China
- Published online on: February 5, 2015 https://doi.org/10.3892/ol.2015.2936
-
Pages:
1764-1766
Metrics: Total
Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
This article is mentioned in:
Abstract
Extramedullary plasmacytoma (EMP) is an uncommon tumor of the plasma cells, and EMP of the cricoid cartilage is extremely rare The present study reports the rare case of a 43‑year‑old male complaining of hoarseness and dyspnea for over a year. Computed tomography imaging of the neck revealed an occupying lesion in the cricoid cartilage, and a diagnosis of EMP was subsequently confirmed by histopathological evaluation. The patient underwent surgery, but refused radiotherapy against medical advice. One year later, the patient was diagnosed with a recurrence of EMP via pathological examination and underwent a second surgery, however, radiotherapy was refused. After a further two years and four months, the patient presented with lumps in the neck, and was subsequently diagnosed with multiple myeloma. The patient received systematic chemotherapy in the hematology department; the patient's general condition stabilized, and no further anemia, bone pain, infection or other discomfort was experienced. Solitary plasmacytoma of the cricoid cartilage is a rare lesion and compliance with radiotherapy following surgery may provide significant benefit in the treatment of this disease.
View References
1
|
Korolkowa O, Osuch-Wójcikiewicz E, Deptała
A and Suleiman W: Extramedullary plasmacytoma of the head and neck.
Otolaryngol Pol. 58:1009–1012. 2004.(In Polish).
|
2
|
Rodriguez-de-Velasquez A, Weber A and
Montgomery W: Extramedullary laryngeal plasmacytoma. Ann Otol
Rhinol Laryngol. 105:483–486. 1996. View Article : Google Scholar : PubMed/NCBI
|
3
|
Hall FT, Perez-Ordonez B and Irish J:
Pathology quiz case 1. Multiple myeloma with an extramedullary
plasmacytoma involving the subglottis. Arch Otolaryngol Head Neck
Surg. 130:366–368. 2004. View Article : Google Scholar : PubMed/NCBI
|
4
|
Pichi B, Terenzi V, Covello R and Spriano
G: Cricoid-based extramedullary plasmocytoma. J Craniofac Surg.
22:2361–2363. 2011. View Article : Google Scholar : PubMed/NCBI
|
5
|
Straetmans J and Stokroos R:
Extramedullary plasmacytomas in the head and neck region. Eur Arch
Otorhinolaryngol. 265:1417–1423. 2008. View Article : Google Scholar : PubMed/NCBI
|
6
|
Ben Salah H, Hdiji S, Makni S, et al:
Extramedullary plasmocytomas. Cancer Radiother. 16:282–287. 2011.
View Article : Google Scholar
|
7
|
Kim KS, Yang HS, Park ES and Bae TH:
Solitary Extramedullary Plasmacytoma of the Apex of Arytenoid:
Endoscopic, CT, and Pathologic Findings. Clin Exp Otorhinolaryngol.
5:107–111. 2012. View Article : Google Scholar : PubMed/NCBI
|
8
|
Miller FR, Lavertu P, Wanamaker JR,
Bonafede J and Wood BG: Plasmacytomas of the head and neck.
Otolaryngol Head Neck Surg. 119:614–618. 1998. View Article : Google Scholar : PubMed/NCBI
|
9
|
Anderson KC, Alsina M, Bensinger W, et al:
Multiple myeloma, version 1.2013. J Natl Compr Canc Netw. 11:11–17.
2013.PubMed/NCBI
|
10
|
Soutar R, Lucraft H, Jackson G, et al;
Guidelines Working Group of the UK Myeloma Forum; British Committee
for Standards in Haematology; British Society for Haematology.
Guidelines on the diagnosis and management of solitary plasmacytoma
of bone and solitary extramedullary plasmacytoma. Br J Haematol.
124. pp. 717–726. 2004, View Article : Google Scholar
|
11
|
Susnerwala SS, Shanks JH, Banerjee SS,
Scarffe JH, Farrington WT and Slevin NJ: Extramedullary
plasmacytoma of the head and the neck region: clinicopathological
correlation in 25 cases. Br J Cancer. 75:921–927. 1997. View Article : Google Scholar
|
12
|
Gerry D and Lentsch EJ: Epidemiologic
evidence of superior outcomes for extramedullary plasmacytoma of
the head and neck. Otolaryngol Head Neck Surg. 148:974–981. 2013.
View Article : Google Scholar : PubMed/NCBI
|
13
|
Tsang RW, Gospodarowicz MK, Pintilie M, et
al: Solitary plasmacytoma treated with radiotherapy: impact of
tumor size on outcome. Int J Radiat Oncol Biol Phys. 50:113–120.
2001. View Article : Google Scholar : PubMed/NCBI
|