1
|
Rothkamm K, Krüger I, Thompson LH and
Löbrich M: Pathways of DNA double-strand break repair during the
mammalian cell cycle. Mol Cell Biol. 23:5706–5715. 2003. View Article : Google Scholar : PubMed/NCBI
|
2
|
Finnie NJ, Gottlieb TM, Blunt T, et al:
DNA-dependent protein kinase activity is absent in xrs-6 cells:
implications for site-specific recombination and DNA double-strand
break repair. Proc Natl Acad Sci USA. 92:320–324. 1995. View Article : Google Scholar : PubMed/NCBI
|
3
|
Peterson SR, Kurimasa A, Oshimura M, et
al: Loss of the catalytic subunit of the DNA-dependent protein
kinase in DNA double-strand-break-repair mutant mammalian cells.
Proc Natl Acad Sci USA. 92:3171–3174. 1995. View Article : Google Scholar : PubMed/NCBI
|
4
|
Kurimasa A, Kumano S, Boubnov NV, et al:
Requirement for the kinase activity of human DNA-dependent protein
kinase catalytic subunit in DNA strand break rejoining. Mol Cell
Biol. 19:3877–3884. 1999.PubMed/NCBI
|
5
|
Chan DW, Chen BP, Prithivirajsingh S, et
al: Autophosphorylation of the DNA-dependent protein kinase
catalytic subunit is required for rejoining of DNA double-strand
breaks. Genes Dev. 16:2333–2338. 2002. View Article : Google Scholar : PubMed/NCBI
|
6
|
Ding Q, Reddy YV, Wang W, et al:
Autophosphorylation of the catalytic subunit of the DNA-dependent
protein kinase is required for efficient end processing during DNA
double-strand break repair. Mol Cell Biol. 23:5836–5848. 2003.
View Article : Google Scholar : PubMed/NCBI
|
7
|
Chen BP, Uematsu N, Kobayashi J, et al:
Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs
phosphorylations at the Thr-2609 cluster upon DNA double strand
break. J Biol Chem. 282:6582–6587. 2007. View Article : Google Scholar
|
8
|
Chen BP, Chan DW, Kobayashi J, et al: Cell
cycle dependence of DNA-dependent protein kinase phosphorylation in
response to DNA double strand breaks. J Biol Chem. 280:14709–14715.
2005. View Article : Google Scholar : PubMed/NCBI
|
9
|
Cui X, Yu Y, Gupta S, Cho YM, Lees-Miller
SP and Meek K: Autophosphorylation of DNA-dependent protein kinase
regulates DNA end processing and may also alter double-strand break
repair pathway choice. Mol Cell Biol. 25:10842–10852. 2005.
View Article : Google Scholar : PubMed/NCBI
|
10
|
Nagasawa H, Little JB, Lin YF, et al:
Differential role of DNA-PKcs phosphorylations and kinase activity
in radiosensitivity and chromosomal instability. Radiat Res.
175:83–89. 2011. View
Article : Google Scholar :
|
11
|
Hada M and Georgakilas AG: Formation of
clustered DNA damage after high-LET irradiation: a review. J Radiat
Res. 49:203–210. 2008. View Article : Google Scholar : PubMed/NCBI
|
12
|
Goodhead DT: Initial events in the
cellular effects of ionizing radiations: clustered damage in DNA.
Int J Radiat Biol. 65:7–17. 1994. View Article : Google Scholar : PubMed/NCBI
|
13
|
Sutherland BM, Bennett PV, Schenk H, et
al: Clustered DNA damages induced by high and low LET radiation,
including heavy ions. Phys Med. 17(Suppl 1): 202–204. 2001.
|
14
|
Sutherland BM, Bennett PV, Weinert E,
Sidorkina O and Laval J: Frequencies and relative levels of
clustered damages in DNA exposed to gamma rays in radioquenching
vs. nonradioquenching conditions. Environ Mol Mutagen. 38:159–165.
2001. View
Article : Google Scholar : PubMed/NCBI
|
15
|
Leatherbarrow EL, Harper JV, Cucinotta FA
and O’Neill P: Induction and quantification of gamma-H2AX foci
following low and high LET-irradiation. Int J Radiat Biol.
82:111–118. 2006. View Article : Google Scholar : PubMed/NCBI
|
16
|
Schmid TE, Dollinger G, Beisker W, et al:
Differences in the kinetics of gamma-H2AX fluorescence decay after
exposure to low and high LET radiation. Int J Radiat Biol.
86:682–691. 2010. View Article : Google Scholar : PubMed/NCBI
|
17
|
Roos WP and Kaina B: DNA damage-induced
cell death by apoptosis. Trends Mol Med. 12:440–450. 2006.
View Article : Google Scholar : PubMed/NCBI
|
18
|
Jung Y and Lippard SJ: Direct cellular
responses to platinum-induced DNA damage. Chem Rev. 107:1387–1407.
2007. View Article : Google Scholar : PubMed/NCBI
|
19
|
Gonzalez VM, Fuertes MA, Alonso C and
Perez JM: Is cisplatin-induced cell death always produced by
apoptosis? Mol Pharmacol. 59:657–663. 2001.PubMed/NCBI
|
20
|
Basu A and Krishnamurthy S: Cellular
responses to cisplatin-induced DNA damage. J Nucleic Acids.
2010:2010. View Article : Google Scholar
|
21
|
Vilenchik MM and Knudson AG: Endogenous
DNA double-strand breaks: production, fidelity of repair, and
induction of cancer. Proc Natl Acad Sci USA. 100:12871–12876. 2003.
View Article : Google Scholar : PubMed/NCBI
|