Undiagnosed giant cystic pheochromocytoma: A case report

Wang,Huan‑Liang; Sun,Bao‑Zhu; Xu,Zhi‑Jie; Lei,Wei‑Fu; Wang,Xiao‑Shuang

doi:10.3892/ol.2015.3484

Undiagnosed giant cystic pheochromocytoma: A case report

Authors:
- Huan‑Liang Wang
- Bao‑Zhu Sun
- Zhi‑Jie Xu
- Wei‑Fu Lei
- Xiao‑Shuang Wang
View Affiliations

Affiliations: Department of Anesthesiology, Qilu Hospital, Shandong University, Jinan, Shandong 250012, P.R. China, College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250012, P.R. China
Published online on: July 10, 2015 https://doi.org/10.3892/ol.2015.3484
Pages: 1444-1446
Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

Giant cystic pheochromocytomas (GPCCs) are rare adrenal tumors and the majority of them present as asymptomatic. As a result GPCCs often remain undiagnosed until surgery and therefore the surgical team face a greater challenge in perioperative management. The present study describes the case of a 36 year‑old woman with an undiagnosed GPCC, which was successfully resected despite the occurrence of perioperative cardiovascular events, including hypertension, hypotension, ventricular arrhythmias, acute heart failure, acute myocardial infarction, and the patient was discharged home without any recurrence. It should be considered in retroperitoneal tumour of patients with nonspecific symptoms and given adequate treatment to promote the perioperative safety.

View Figures

View References

1	Dahia PL: Evolving concepts in pheochromocytoma and paraganglioma. Curr Opin Oncol. 18:1–8. 2006. View Article : Google Scholar : PubMed/NCBI
2	Elder EE, Elder G and Larsson C: Pheochromocytoma and functional paraganglioma syndrome: No longer the 10% tumor. J Surg Oncol. 89:193–201. 2005. View Article : Google Scholar : PubMed/NCBI
3	Li C, Chen Y, Wang W and Teng L: A case of clinically silent giant right pheochromocytoma and review of literature. Can Urol Assoc J. 6:E267–E269. 2012.PubMed/NCBI
4	Lee TH, Slywotsky CM, Lavelle MT and Garcia RA: Cystic pheochromocytoma. Radiographics. 22:935–940. 2002. View Article : Google Scholar : PubMed/NCBI
5	Neumann HP, Berger DP, Sigmund G, Blum U, Schmidt D, Parmer RJ, Volk B and Kirste G: Pheochromocytomas, multiple endocrine neoplasia type 2 and von Hippel-Lindau disease. N Engl J Med. 329:1531–1538. 1993. View Article : Google Scholar : PubMed/NCBI
6	Pan Z, Repertinger S, Deng C and Sharma P: A giant cystic pheochromocytoma of the adrenal gland. Endocr Pathol. 19:133–138. 2008. View Article : Google Scholar : PubMed/NCBI
7	Antedomenico E and Wascher RA: A case of mistaken identity: Giant cystic pheochromocytoma. Curr Surg. 62:193–198. 2005. View Article : Google Scholar : PubMed/NCBI
8	Wu JS, Ahya SN, Reploeg MD, Singer GG, Brennan DC, Howard TK and Lowell JA: Pheochromocytoma presenting as a giant cystic tumor of the liver. Surgery. 128:482–484. 2000. View Article : Google Scholar : PubMed/NCBI
9	Terk MR, de Verdier H and Colletti PM: Giant extra-adrenal pheochromocytoma: Magnetic resonance imaging with gadolinium-DTPA enhancement. Magn Reson Imaging. 11:47–50. 1993. View Article : Google Scholar : PubMed/NCBI
10	Melegh Z, Rényi-Vámos F, Tanyay Z, Köves I and Orosz Z: Giant cystic pheochromocytoma located in the renal hilus. Pathol Res Pract. 198:103–106. 2002. View Article : Google Scholar : PubMed/NCBI
11	Chan FK, Choi KL, Tiu SC, Shek CC and Au Yong TK: A case of giant malignant phaeochromocytoma. Hong Kong Med J. 6:325–328. 2000.PubMed/NCBI
12	Grissom JR, Yamase HT and Prosser PR: Giant pheochromocytoma with sarcoidosis. South Med J. 72:1605–1607. 1979. View Article : Google Scholar : PubMed/NCBI
13	Awada SH, Grisham A and Woods SE: Large dopamine-secreting pheochromocytoma: Case report. South Med J. 96:914–917. 2003. View Article : Google Scholar : PubMed/NCBI
14	Pacak K, Eisenhofer G, Ahlman H, Bornstein SR, Gimenez-Roqueplo AP, Grossman AB, Kimura N, Mannelli M, McNicol AM and Tischler AS: International Symposium on Pheochromocytoma: Pheochromocytoma: Recommendations for clinical practice from the First international Symposium. Nat Clin Pract Endocrinol Metab. 3:92–102. 2007. View Article : Google Scholar : PubMed/NCBI
15	Basiri A and Radfar MH: Giant cystic pheochromocytoma. Urol J. 7:162010.PubMed/NCBI
16	Costa SR, Cabral NM, Abhrão AT, Costa RB, Silva LM and Lupinacci RA: Giant cystic malignant pheochromocytoma invading right hepatic lobe: Report on two cases. Sao Paulo Med J. 126:229–231. 2008. View Article : Google Scholar : PubMed/NCBI
17	Tarant NS, Dacanay RG, Mecklenburg BW, Birmingham SD, Lujan E and Green R: Acute appendicitis in a patient with undiagnosed pheochromocytoma. Anesth Analg. 102:642–643. 2006. View Article : Google Scholar : PubMed/NCBI