Synchronous double primary cancer ‑ intrahepatic cholangiocarcinoma with bone metastases and thyroid carcinoma: A case report

Wang,Qing‑Liang; Li,Xiao‑Jie; Zhao,Kun; Liu,Bo; Ye,Xiao‑Ming

doi:10.3892/ol.2015.3822

Synchronous double primary cancer ‑ intrahepatic cholangiocarcinoma with bone metastases and thyroid carcinoma: A case report

Authors:
- Qing‑Liang Wang
- Xiao‑Jie Li
- Kun Zhao
- Bo Liu
- Xiao‑Ming Ye
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Affiliations: Department of General Surgery, Ling Nan Hospital, The Third Affiliated Hospital of Sun Yat‑Sen University, Guangzhou, Guangdong 510530, P.R. China, Department of Laboratory Medicine, Ling Nan Hospital, The Third Affiliated Hospital of Sun Yat‑Sen University, Guangzhou, Guangdong 510530, P.R. China
Published online on: October 20, 2015 https://doi.org/10.3892/ol.2015.3822
Pages: 3799-3802

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Abstract

There is a low incidence of multiple primary cancer, particularly when the cancer is synchronous. The present report presents a case of synchronous double primary malignancies. A 58-year-old woman was admitted to Ling Nan Hospital (Guangzhou, China) complaining of pain in the left hip. X‑ray revealed an osteolytic lesion and further examination indicated the presence of double primary cancer, consisting of hepatic cholangiocarcinoma and thyroid carcinoma. Biopsy of the osteolytic lesion showed a metastatic adenocarcinoma of unknown origin. Subsequently, final diagnosis was confirmed by I‑131 scan and liver lesion biopsy. The patient received positive multidisciplinary treatments and survived for 9 months following diagnosis. The results of the present case suggest that multiplicity of primary malignancy is not necessarily an indicator of poor prognosis, as long as effective diagnosis and adequate disease management are achieved.

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