Prostatic adenocarcinoma presenting with metastases to the testis and epididymis: A case report

  • Authors:
    • Jin Zhang
    • Mei Dong
    • Xiaolei Hu
    • Lin Liu
    • Shen Li
    • Chao Li
    • Lijun Yang
    • Yongqiang Xiao
    • Shujian Pang
    • Chuan Wang
  • View Affiliations

  • Published online on: November 16, 2015     https://doi.org/10.3892/ol.2015.3920
  • Pages: 792-794
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Abstract

Few cases of testicular metastases from prostate carcinoma have been reported, and asymptomatic metastases of prostate carcinoma to both the testis and epididymis are extremely rare. The current study presents the case of a 69-year-old male with testicular and epididymal metastases from prostate carcinoma. The patient was admitted to The First Hospital of Shijiazhuang with a 2-year history of lower urinary tract symptoms. Digital rectal examination revealed an enlarged multinodular prostate, and the serum prostate-specific antigen (PSA) level was >100 ng/ml. Magnetic resonance imaging showed prostate carcinoma with seminal vesicle involvement. A prostate biopsy showed prostate gland adenocarcinoma. The Gleason score was 3+3. The immunohistochemistry results were as follows: Prostatic acid phosphatase (+++), PSA (+++), P504s (+++), p63 (-) and cytokeratin 34βE12 (-), with a Ki-67 of ~5%. The patient was treated with a bilateral orchiectomy. The testicular pathology showed that the right testis and epididymis were invaded with metastatic adenocarcinoma. The left testis and epididymis were normal. The patient was treated with conventional flutamide endocrine therapy. At present the patient remains in a stable condition after 24 months of follow-up.
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January-2016
Volume 11 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Zhang J, Dong M, Hu X, Liu L, Li S, Li C, Yang L, Xiao Y, Pang S, Wang C, Wang C, et al: Prostatic adenocarcinoma presenting with metastases to the testis and epididymis: A case report. Oncol Lett 11: 792-794, 2016.
APA
Zhang, J., Dong, M., Hu, X., Liu, L., Li, S., Li, C. ... Wang, C. (2016). Prostatic adenocarcinoma presenting with metastases to the testis and epididymis: A case report. Oncology Letters, 11, 792-794. https://doi.org/10.3892/ol.2015.3920
MLA
Zhang, J., Dong, M., Hu, X., Liu, L., Li, S., Li, C., Yang, L., Xiao, Y., Pang, S., Wang, C."Prostatic adenocarcinoma presenting with metastases to the testis and epididymis: A case report". Oncology Letters 11.1 (2016): 792-794.
Chicago
Zhang, J., Dong, M., Hu, X., Liu, L., Li, S., Li, C., Yang, L., Xiao, Y., Pang, S., Wang, C."Prostatic adenocarcinoma presenting with metastases to the testis and epididymis: A case report". Oncology Letters 11, no. 1 (2016): 792-794. https://doi.org/10.3892/ol.2015.3920