Malignant intrasellar meningioma presenting as an invasive pituitary macroadenoma: A rare case report and literature review

Zhou,Peizhi; Yin,Senlin; Jiang,Shu; Cai,Bowen

doi:10.3892/ol.2015.4027

Malignant intrasellar meningioma presenting as an invasive pituitary macroadenoma: A rare case report and literature review

Authors:
- Peizhi Zhou
- Senlin Yin
- Shu Jiang
- Bowen Cai
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Affiliations: Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China
Published online on: December 11, 2015 https://doi.org/10.3892/ol.2015.4027
Pages: 1073-1076

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Abstract

Intrasellar meningiomas are rare tumors that have the ability to mimic non-functioning pituitary adenomas. The majority of meningiomas are slow‑growing and benign, therefore an intrasellar meningioma with malignant histological features is extremely rare. The present study describes the case of a malignant diaphragm meningioma that was controlled through combined chemotherapy, following subtotal surgical resection. The patient's symptoms ceased and no tumor recurrence was detected at the 3‑year follow‑up. Hormone levels were also observed as normal. Further investigation of similar cases may aid in achieving an accurate pre‑operative diagnosis. This would prove particularly beneficial in regards to intrasellar meningiomas due to their specific location and surgical treatment. The present study analyzes the requirement of chemotherapy for the treatment of these unique tumors.

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1	Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW and Kleihues P: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 114:97–109. 2007. View Article : Google Scholar : PubMed/NCBI
2	Nozaki K, Nagata I, Yoshida K and Kikuchi H: Intrasellar meningioma, Case report and review of the literature. Surg Neurol. 47:447–454. 1997. View Article : Google Scholar : PubMed/NCBI
3	Pinzer T, Krishnan KG and Schackert G: The diaphragma sellae meningioma - a rare differential diagnosis of non-functioning pituitary adenoma. Zentralbl Neurochir. 65:195–197. 2004. View Article : Google Scholar : PubMed/NCBI
4	Valassi E, Biller BM, Klibanski A and Swearingen B: Clinical features of nonpituitary sellar lesions in a large surgical series. Clin Endocrinol (Oxf). 73:798–807. 2010. View Article : Google Scholar : PubMed/NCBI
5	Matsumoto S, Hayase M, Imamura H, Oda Y, Kikuchi H, Katayama M and Ishihara T: A case of intrasellar meningioma mimicking pituitary adenoma. No Shinkei Geka. 29:551–557. 2001.(In Japanese). PubMed/NCBI
6	Rogers L, Gilbert M and Vogelbaum MA: Intracranial meningiomas of atypical (WHO grade II) histology. J Neurooncol. 99:393–405. 2010. View Article : Google Scholar : PubMed/NCBI
7	Orakdöğeny M, Karadereler S, Berkman Z, Erşahin M, Ozdoğan C and Aker F: Intra-suprasellar meningioma mimicking pituitary apoplexy. Acta Neurochir (Wien). 146:511–515. 2004. View Article : Google Scholar : PubMed/NCBI
8	Satoh H, Arita K, Kurisu K, Sumida M, Nakahara T, Eguchi K and Kuroki K: Intrasellar meningioma, Characteristic imaging findings. Neuroradiology. 38:328–329. 1996. View Article : Google Scholar : PubMed/NCBI
9	Watanabe M, Toyama M, Watanabe M, Taniguchi Y, Kaneko K and Yokoyama M: A case of intrasellar meningioma with panhypopituitarism and hyperprolactinemia. No Shinkei Geka. 15:869–874. 1987.(In Japanese). PubMed/NCBI
10	Nagao S, Kawai N, Ohomoto T and Oohashi T: A case of intrasellar and suprasellar meningioma with hypopituitarism. No Shinkei Geka. 18:637–642. 1990.(In Japanese). PubMed/NCBI
11	Ildan F: Recurrent intrasellar meningioma after total excision in a woman with hyperprolactinaemia. Turkish Neurosurg. 4:93–97. 1994.
12	Yoneoka Y, Tanaka R, Minakawa T and Tamura T: Psammomatous meningioma arising from the diaphragma sellae. Acta Neurochir (Wien). 140:291–292. 1998. View Article : Google Scholar : PubMed/NCBI
13	Kudo H, Takaishi Y, Minami H, Takamoto T, Kitazawa S, Maeda S and Tamaki N: Intrasellar meningioma mimicking pituitary apoplexy, Case report. Surg Neurol. 48:374–381. 1997. View Article : Google Scholar : PubMed/NCBI
14	Kinjo T, al-Mefty O and Ciric I: Diaphragma sellae meningiomas. Neurosurgery. 36:1082–1092. 1995. View Article : Google Scholar : PubMed/NCBI
15	Cushing H: The meningiomas (dural endotheliomas): Their source and favoured seats of origin. Brain. 45:282–316. 1922. View Article : Google Scholar
16	Sade B, Chahlavi A, Krishnaney A, Nagel S, Choi E and Lee JH: World Health Organization Grades II and III meningiomas are rare in the cranial base and spine. Neurosurgery. 61:1194–1198. 2007. View Article : Google Scholar : PubMed/NCBI
17	Grisoli F, Vincentelli F, Raybaud C, Harter M, Guibout M and Baldini M: Intrasellar meningioma. Surg Neurol. 20:36–41. 1983. View Article : Google Scholar : PubMed/NCBI
18	Hardy J and Robert F: A meningioma of the sella turcica subdiaphragmatic variety. Histopathology. Neurochirurgie. 15:535–543. 1969.(In French). PubMed/NCBI
19	Perry A, Gutmann DH and Reifenberger G: Molecular pathogenesis of meningiomas. J Neurooncol. 70:183–202. 2004. View Article : Google Scholar : PubMed/NCBI
20	Wen PY, Quant E, Drappatz J, Beroukhim R and Norden AD: Medical therapies for meningiomas. J Neurooncol. 99:365–378. 2010. View Article : Google Scholar : PubMed/NCBI