A case of myeloproliferative neoplasm with a normal complete blood cell count: A novel problem of the JAK2 era

  • Authors:
    • Xiu‑Peng Ye
    • Shen Bao
    • Huan‑Min Gao
    • Ying Guo
    • Yu‑Ping Wei
  • View Affiliations

  • Published online on: February 8, 2016     https://doi.org/10.3892/ol.2016.4192
  • Pages: 2134-2136
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Abstract

The present study reported a case of a myeloproliferative neoplasm (MPN) in a patient with a normal complete blood cell count. Bone marrow biopsy showed bone marrow hyperplasia, an elevated megakaryocyte count, megakaryocytic dysplasia and pleomorphic changes, multiple megakaryocyte clusters and focal reticulin fiber hyperplasia. Furthermore, genetic analysis revealed that the patient was positive for the JAK2‑V617F mutation, and negative for the JAK2 exon 12 and 13 mutations and the BCR‑ABL (p210) fusion gene. The patient's condition was basically stable and at the time of writing, the patient remained in a stable condition with no specific symptoms of disease. The present study also analyzed the diagnostic and clinical features of MPNs, and a literature review was performed. MPN with a normal complete blood cell count is a rare disease, and attention should be focused on this entity in the clinic.
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March-2016
Volume 11 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Ye XP, Bao S, Gao HM, Guo Y and Wei YP: A case of myeloproliferative neoplasm with a normal complete blood cell count: A novel problem of the JAK2 era. Oncol Lett 11: 2134-2136, 2016.
APA
Ye, X., Bao, S., Gao, H., Guo, Y., & Wei, Y. (2016). A case of myeloproliferative neoplasm with a normal complete blood cell count: A novel problem of the JAK2 era. Oncology Letters, 11, 2134-2136. https://doi.org/10.3892/ol.2016.4192
MLA
Ye, X., Bao, S., Gao, H., Guo, Y., Wei, Y."A case of myeloproliferative neoplasm with a normal complete blood cell count: A novel problem of the JAK2 era". Oncology Letters 11.3 (2016): 2134-2136.
Chicago
Ye, X., Bao, S., Gao, H., Guo, Y., Wei, Y."A case of myeloproliferative neoplasm with a normal complete blood cell count: A novel problem of the JAK2 era". Oncology Letters 11, no. 3 (2016): 2134-2136. https://doi.org/10.3892/ol.2016.4192