Open Access

An unresectable retroperitoneal malignant fibrous histiocytoma: A case report

  • Authors:
    • Po‑Jen Hsiao
    • Guang‑Heng Chen
    • Yi‑Huei Chang
    • Chao‑Hsiang Chang
    • Han Chang
    • Li‑Yuan Bai
  • View Affiliations

  • Published online on: February 25, 2016     https://doi.org/10.3892/ol.2016.4283
  • Pages: 2403-2407
  • Copyright: © Hsiao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Malignant fibrous histiocytoma (MFH) is most commonly observed in the extremities and the trunk but rarely in retroperitoneum. The present case report documents a 64‑year‑old man who was admitted with an abdominal palpable mass for 6 months. After a thorough investigation, a tumor of the retroperitoneum was identified adhered to adjacent organs and vessels. The patient experienced mild hydronephrosis and hydroureter as a result of the tumor compression. A number of previous surgeons considered the tumor unresectable and suggested palliative treatment. En bloc resection of the tumor was attempted but incomplete surgery was performed initially as the tumor was friable and prone to bleeding. Therefore, a biopsy of the tumor was performed and a double J ureteral stent was set for hydronephrosis. Histopathological examination confirmed the tumor was an MFH. The patient received neo‑adjuvant chemotherapy with 4 cycles of mesna, doxorubicin, ifosfamide, and dacarbazine (MAID). A computed tomography scan demonstrated that the tumor had reduced in size following chemotherapy. En bloc resection of the tumor was arranged again 6 months later. The tumor exhibited a complete response to neo‑adjuvant chemotherapy after the formal pathological evaluation. The patient survives without tumor recurrence >5 years without recurrence.
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April-2016
Volume 11 Issue 4

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Hsiao PJ, Chen GH, Chang YH, Chang CH, Chang H and Bai LY: An unresectable retroperitoneal malignant fibrous histiocytoma: A case report. Oncol Lett 11: 2403-2407, 2016.
APA
Hsiao, P., Chen, G., Chang, Y., Chang, C., Chang, H., & Bai, L. (2016). An unresectable retroperitoneal malignant fibrous histiocytoma: A case report. Oncology Letters, 11, 2403-2407. https://doi.org/10.3892/ol.2016.4283
MLA
Hsiao, P., Chen, G., Chang, Y., Chang, C., Chang, H., Bai, L."An unresectable retroperitoneal malignant fibrous histiocytoma: A case report". Oncology Letters 11.4 (2016): 2403-2407.
Chicago
Hsiao, P., Chen, G., Chang, Y., Chang, C., Chang, H., Bai, L."An unresectable retroperitoneal malignant fibrous histiocytoma: A case report". Oncology Letters 11, no. 4 (2016): 2403-2407. https://doi.org/10.3892/ol.2016.4283