Primary non-Hodgkin lymphoma of the sphenoid sinus with visual disturbance: A report of two cases

Ye,Huiping; Gong,Zhengpeng; Yang,Wen; Dai,Yubing

doi:10.3892/ol.2016.4534

Primary non-Hodgkin lymphoma of the sphenoid sinus with visual disturbance: A report of two cases

Authors:
- Huiping Ye
- Zhengpeng Gong
- Wen Yang
- Yubing Dai
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Affiliations: Department of Otolaryngology, Head and Neck Surgery, The Affiliated Baiyun Hospital of Guizhou Medical University, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China, Department of Pathology, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China, Department of Otolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China
Published online on: May 6, 2016 https://doi.org/10.3892/ol.2016.4534
Pages: 4252-4254

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Abstract

Primary non-Hodgkin lymphoma (PNHL) of the sphenoid sinus is a rare neoplasm that poses a diagnostic challenge to clinicians. The proximity of the optical nerve and canal to the sphenoid sinus is accountable for the high incidence of visual disturbance in PNHL of the sphenoid sinus. In particular, patients whose radiologic diagnosis reveals bone destruction in the lateral wall involved with optical‑nerve‑canals or cavernous sinus present a high risk of rapidly developing unilateral blindness. The present study reports 2 rare cases of PNHL of the sphenoid sinus. Sudden sight loss may follow minimally invasive biopsy. In such cases, the measures that must be taken for the prevention of permanent sight loss are limited in the absence of the final pathologic diagnosis.

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1	Abbondanzo SL and Wenig BM: Non-Hodgkins lymphoma of the sinonasal tract. A clinicopathologic and immunophenotypic study of 120 cases. Cancer. 75:1281–1291. 1995. View Article : Google Scholar : PubMed/NCBI
2	Yasumoto M, Taura S, Shibuya H and Honda M: Primary malignant lymphoma of the maxillary sinus: CT and MRI. Neuroradiology. 42:285–289. 2000. View Article : Google Scholar : PubMed/NCBI
3	Lee H, Choi KE, Park M, Lee SH and Baek S: Primary diffuse large B-cell non-Hodgkin lymphoma of the paranasal sinuses presenting as cavernous sinus syndrome. J Craniofac Surg. 25:e338–e339. 2014. View Article : Google Scholar : PubMed/NCBI
4	Peng KA, Kita AE, Suh JD, Bhuta SM and Wang MB: Sinonasal lymphoma: Case series and review of the literature. Int Forum Allergy Rhinol. 4:670–674. 2014. View Article : Google Scholar : PubMed/NCBI
5	Bhatia A, Saikia UN, Kumar Y and Dey P: Fine needle aspiration cytology of spindle cell variant of diffuse large B-cell lymphoma: A diagnostic dilemma. Cytopathology. 19:197–199. 2008. View Article : Google Scholar : PubMed/NCBI
6	Mubarak A, Wolters VM, Houwen RH and ten Kate FJ: Immunohistochemical CD3 staining detects additional patients with celiac disease. World J Gastroenterol. 21:7553–7557. 2015. View Article : Google Scholar : PubMed/NCBI
7	Alexander FW: Primary tumors of the sphenoid sinus. Laryngoscope. 73:537–546. 1963. View Article : Google Scholar : PubMed/NCBI
8	Lawson W and Reino AJ: Isolated sphenoid sinus disease: An analysis of 132 cases. Laryngoscope. 107:1590–1595. 1997. View Article : Google Scholar : PubMed/NCBI
9	Roth DB and Siatkowski RM: Bilateral blindness as the initial presentation of lymphoma of the sphenoid sinus. Am J Ophthalmol. 129:256–258. 2000. View Article : Google Scholar : PubMed/NCBI
10	Kim GE, Koom WS, Yang WI, Lee SW, Keum KC, Lee CG, Suh CO, Hahn JS, Roh JK and Kim JH: Clinical relevance of three subtypes of primary sinonasal lymphoma characterized by immunophenotypic analysis. Head Neck. 26:584–593. 2004. View Article : Google Scholar : PubMed/NCBI
11	Yen TT, Wang RC, Jiang RS, Chen SC, Wu SH and Liang KL: The diagnosis of sinonasal lymphoma: A challenge for rhinologists. Eur Arch Otorhinolaryngol. 269:1463–1469. 2012. View Article : Google Scholar : PubMed/NCBI
12	Bisdas S, Fetscher S, Feller AC, Baghi M, Knecht R, Gstoettner W, Vogl TJ and Balzer JO: Primary B cell lymphoma of the sphenoid sinus: CT and MRI characteristics with correlation to perfusion and spectroscopic imaging features. Eur Arch Otorhinolaryngol. 264:1207–1213. 2007. View Article : Google Scholar : PubMed/NCBI
13	Park YM, Cho JH, Cho JY, Huh JS and Ahn JY: Non-Hodgkins lymphoma of the sphenoid sinus presenting as isolated oculomotor nerve palsy. World J Surg Oncol. 5:862007. View Article : Google Scholar : PubMed/NCBI
14	Kitthaweesin K and Theerakul T: Neuro-ophthalmic manifestations in sinusitis patients who underwent endoscopic sinus surgery. J Med Assoc Thai. 95:1543–1547. 2012.PubMed/NCBI
15	Inaki S, Okamura H and Chikamori Y: Adult T-cell leukemia/lymphoma originating in the paranasal sinus. Arch Otolaryngol Head Neck Surg. 114:1471–1473. 1988. View Article : Google Scholar : PubMed/NCBI
16	Touitou V, LeHoang P and Bodaghi B: Primary CNS lymphoma. Curr Opin Ophthalmol. 26:526–533. 2015. View Article : Google Scholar : PubMed/NCBI