Renal oncocytoma: A report of two cases and review of the literature

Wang,Yuantao; Hu,Yu; Zhai,Xiuyu; Wang,Weigang; Dong,Biao; Zhou,Honglan

doi:10.3892/ol.2016.4594

Renal oncocytoma: A report of two cases and review of the literature

Authors:
- Yuantao Wang
- Yu Hu
- Xiuyu Zhai
- Weigang Wang
- Biao Dong
- Honglan Zhou
View Affiliations

Affiliations: Department of Urology, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China, Department of Pathology, China-Japan Union Hospital, Jilin University, Changchun, Jilin 130033, P.R. China, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China
Published online on: May 17, 2016 https://doi.org/10.3892/ol.2016.4594
Pages: 291-294

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

Renal oncocytoma is one of the most unusual benign lesion, which are usually diagnosed postoperatively, since their differentiation from renal cell carcinoma is challenging. The present study reports two cases of renal oncocytoma in a 60‑year‑old woman and a 46‑year‑old man. Relevant clinical and pathological data on the two patients were retrieved. The tumors were excised and the patients underwent laparoscopic radical nephrectomy. Typical features of oncocytoma were observed upon histological examination of the excised specimens. The postoperative course of each patient was uneventful and they were discharged 8 and 7 days post‑surgery, respectively. In addition, the current study presents the results of a literature review regarding the radiological, immunohistochemical and pathological characteristics of renal oncocytoma.

View Figures

View References

1	Morra MN and Das S: Renal oncocytoma: A review of histogenesis, histopathology, diagnosis and treatment. J Urol. 150:295–302. 1993.PubMed/NCBI
2	Alamara C, Karapanagiotou EM, Tourkantonis I, Xyla V, Maurer CC, Lykourinas M, Pandha H and Syrigos KN: Renal oncocytoma: A case report and short review of the literature. Eur J Intern Med. 19:e67–e69. 2008. View Article : Google Scholar : PubMed/NCBI
3	Perez-Ordonez B, Hamed G, Campbell S, Erlandson RA, Russo P, Gaudin PB and Reuter VE: Renal oncocytoma: a clinicopathologic study of 70 cases. Am J Surg Pathol. 21:871–883. 1997. View Article : Google Scholar : PubMed/NCBI
4	Koller A, Kain R, Haitel A, Mazal PR, Asboth F and Susani M: Renal oncocytoma with prominent intracytoplasmic vacuoles of mitochondrial origin. Histopathology. 37:264–268. 2000. View Article : Google Scholar : PubMed/NCBI
5	Fan YH, Chang YH, Huang WJ, Chung HJ and Chen KK: Renal oncocytoma: Clinical experience of Taipei Veterans General Hospital. J Chin Med Assoc. 71:254–258. 2008. View Article : Google Scholar : PubMed/NCBI
6	Banks KL, Cherullo EE and Novick AC: Giant renal oncocytoma. Urology. 57:3652001. View Article : Google Scholar : PubMed/NCBI
7	Ahmad S, Manecksha R, Hayes BD and Grainger R: Case report of a symptomatic giant renal oncocytoma. Int J Surg Case Rep. 2:83–85. 2011. View Article : Google Scholar : PubMed/NCBI
8	Romis L, Cindolo L, Patard JJ, Messina G, Altieri V, Salomon L, Abbou CC, Chopin D, Lobel B and de La Taille A: Frequency, clinical presentation and evolution of renal oncocytomas: Multicentric experience from a European database. Eur Urol. 45:53–57; discussion 57. 2004. View Article : Google Scholar : PubMed/NCBI
9	Ciftci AO, Talim B, Senocak ME, Kaymaz F, Cağlar M and Büyükpamukçu N: Renal oncocytoma: Diagnostic and therapeutic aspects. J Pediatr Surg. 35:1396–1398. 2000. View Article : Google Scholar : PubMed/NCBI
10	Avery AK, Beckstead J, Renshaw AA and Corless CL: Use of antibodies to RCC and CD10 in the differential diagnosis of renal neoplasms. Am J Surg Pathol. 24:203–210. 2000. View Article : Google Scholar : PubMed/NCBI
11	Langner C, Ratschek M, Rehak P, Schips L and Zigeuner R: CD10 is a diagnostic and prognostic marker in renal malignancies. Histopathology. 45:460–467. 2004. View Article : Google Scholar : PubMed/NCBI
12	Leroy X, Moukassa D, Copin MC, Saint F, Mazeman E and Gosselin B: Utility of cytokeratin 7 for distinguishing chromophobe renal cell carcinoma from renal oncocytoma. Eur Urol. 37:484–487. 2000. View Article : Google Scholar : PubMed/NCBI
13	Dechet CB, Bostwick DG, Blute ML, Bryant SC and Zincke H: Renal oncocytoma: Multifocality, bilateralism, metachronous tumor development and coexistent renal cell carcinoma. J Urol. 162:40–42. 1999. View Article : Google Scholar : PubMed/NCBI