Positive response of a primary malignant pericardial mesothelioma to pemetrexed plus cisplatin followed by pemetrexed maintenance chemotherapy: A case report

  • Authors:
    • Sang Mi Chung
    • Seong Ji Choi
    • Min Jung Kim
    • Jung Yoon Choi
    • Hong Jun Kim
    • Suk‑Young Lee
    • Eun Joo Kang
  • View Affiliations

  • Published online on: May 17, 2016     https://doi.org/10.3892/ol.2016.4598
  • Pages: 213-216
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Abstract

Primary malignant pericardial mesothelioma (PMPM) is a rare tumor with poor prognosis. Surgery is the treatment of choice, but numerous cases are inoperable. For the treatment of inoperable or metastatic cases, systemic chemotherapy is required. However, a standard chemotherapeutic regimen for the treatment of pericardial mesothelioma has not yet been established. Chemotherapy involving pemetrexed and cisplatin has been actively used in the treatment of pleural or peritoneal mesothelioma, and may be considered for the treatment of PMPM. The present study reports the case of a patient with PMPM with lung metastasis who demonstrated a positive response to treatment with pemetrexed and cisplatin followed by pemetrexed maintenance chemotherapy, leading to prolonged progression‑free survival for 21 months.
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July-2016
Volume 12 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Chung SM, Choi SJ, Kim MJ, Choi JY, Kim HJ, Lee SY and Kang EJ: Positive response of a primary malignant pericardial mesothelioma to pemetrexed plus cisplatin followed by pemetrexed maintenance chemotherapy: A case report. Oncol Lett 12: 213-216, 2016.
APA
Chung, S.M., Choi, S.J., Kim, M.J., Choi, J.Y., Kim, H.J., Lee, S., & Kang, E.J. (2016). Positive response of a primary malignant pericardial mesothelioma to pemetrexed plus cisplatin followed by pemetrexed maintenance chemotherapy: A case report. Oncology Letters, 12, 213-216. https://doi.org/10.3892/ol.2016.4598
MLA
Chung, S. M., Choi, S. J., Kim, M. J., Choi, J. Y., Kim, H. J., Lee, S., Kang, E. J."Positive response of a primary malignant pericardial mesothelioma to pemetrexed plus cisplatin followed by pemetrexed maintenance chemotherapy: A case report". Oncology Letters 12.1 (2016): 213-216.
Chicago
Chung, S. M., Choi, S. J., Kim, M. J., Choi, J. Y., Kim, H. J., Lee, S., Kang, E. J."Positive response of a primary malignant pericardial mesothelioma to pemetrexed plus cisplatin followed by pemetrexed maintenance chemotherapy: A case report". Oncology Letters 12, no. 1 (2016): 213-216. https://doi.org/10.3892/ol.2016.4598