Thyroid adenoma and nasopharyngeal carcinoma with metastasis to cervical lymph nodes is misdiagnosed and treated for thyroid carcinoma: A case report
- Authors:
- Miao Zhang
- Heng Wang
- Xuefeng Pan
- Wenbin Wu
- Hui Zhang
-
View Affiliations
Affiliations: Department of Thoracic Surgery, Xuzhou Central Hospital Affiliated to Southeast University, Xuzhou, Jiangsu 221009, P.R. China
- Published online on: May 20, 2016 https://doi.org/10.3892/ol.2016.4612
-
Pages:
553-555
-
Copyright: © Zhang
et al. This
is an open access article distributed under the
terms of Creative
Commons Attribution License.
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Abstract
Lymph node metastasis of nasopharyngeal carcinoma follows an orderly pattern, and diagnosis of nasopharyngeal carcinoma is often made by lymph node biopsy. In the present study, following neck palpation, ultrasonography and cervical computer tomography, a 52‑year‑old female patient with thyroid adenoma and enlarged cervical lymph nodes was misdiagnosed as thyroid carcinoma without undergoing preoperative biopsy, followed by unnecessary total thyroidectomy. Systematic CT scan and nasal endoscopic biopsy confirmed the correct diagnosis of primary NPC concurrent with thyroid adenoma. The patient received palliative radiotherapy and L-thyroxine substitution therapy, and was followed up closely via internet-based approaches with life-style intervention, medication consultation and psychological support for improvement of life quality after radiotherapy. In conclusion, primary malignancies with thyroid metastasis must be considered in the differential diagnosis of thyroid tumors with enlarged cervical lymph nodes.
View References
|
1
|
Chua ML, Wee JT, Hui EP and Chan AT:
Nasopharyngeal carcinoma. Lancet. 387:1012–1024. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Ho FC, Tham IW, Earnest A, Lee KM and Lu
JJ: Patterns of regional lymph node metastasis of nasopharyngeal
carcinoma: A meta-analysis of clinical evidence. BMC Cancer.
12:982012. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Remonti LR, Kramer CK, Leitão CB, Pinto LC
and Gross JL: Thyroid ultrasound features and risk of carcinoma: A
systematic review and meta-analysis of observational studies.
Thyroid. 25:538–550. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Chiumento C, Fiorentino A, Castaldo G and
Fusco V: A case of thyroid metastasis of nasopharyngeal cancer.
Tumori. 97:24e–6e. 2011.PubMed/NCBI
|
|
5
|
Fan TY, Xing J, Lu J, Liu TH, Xu M, Zhang
YJ, Shao Q, Li JB and Yu JM: Phase I/II study of induction
chemotherapy plus concurrent chemotherapy and SMART-IMRT-based
radiotherapy in locoregionally-advanced nasopharyngeal cancer.
Oncol Lett. 5:889–895. 2013.PubMed/NCBI
|
|
6
|
Shi Q, Shen C, Kong L, Wang X, Ding J, Gao
Y, Xu T and Hu C: Involvement of both cervical lymph nodes and
retropharyngeal lymph nodes has prognostic value for N1 patients
with nasopharyngeal carcinoma. Radiat Oncol. 9:72014. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Chung AY, Tran TB, Brumund KT, Weisman RA
and Bouvet M: Metastases to the thyroid: A review of the literature
from the last decade. Thyroid. 22:258–268. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Hegerova L, Griebeler ML, Reynolds JP,
Henry MR and Gharib H: Metastasis to the thyroid gland: report of a
large series from the Mayo Clinic. Am J Clin Oncol. 38:338–342.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Yoon JH, Kwak JY, Kim EK, Moon HJ, Kim MJ,
Kim JY, Koo HR and Kim MH: How to approach thyroid nodules with
indeterminate cytology. Ann Surg Oncol. 17:2147–2155. 2010.
View Article : Google Scholar : PubMed/NCBI
|
