Pituicytoma: A report of three cases and literature review

Yang,Xiaoyu; Liu,Xiaoliang; Li,Wensen; Chen,Dawei

doi:10.3892/ol.2016.5119

Pituicytoma: A report of three cases and literature review

Authors:
- Xiaoyu Yang
- Xiaoliang Liu
- Wensen Li
- Dawei Chen
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Affiliations: Department of Neurosurgery, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China
Published online on: September 12, 2016 https://doi.org/10.3892/ol.2016.5119
Pages: 3417-3422

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Abstract

Pituicytoma is a rare tumor of the sellar and suprasellar regions, arising from the pituicytes, which are specialized glial cells in the neurohypophysis and infundibulum. Due to its rarity, ambiguity persists over the diagnosis, management and prognosis of pituicytoma. The current study presents a case series of three patients, each with a histopathological diagnosis of pituicytoma. A summary of the clinical manifestations, radiological characteristics, histopathological features, treatment strategies and prognoses are presented. In addition, 78 cases of pituicytoma, identified in a search of the published literature in Pubmed, are profiled. Pituicytoma typically presents with dysfunction of the optic nerve and pituitary. The radiological characteristics are nonspecific; diagnosis is typically made on the basis of histopathological results. The tumor is slow growing and benign and is amenable to surgical treatment by gross total resection; subsequent tumor recurrence is rare. A definitive assessment of prognosis requires an extended follow‑up in a larger cohort.

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