Open Access

Langerhans cell sarcoma originating from left knee subcutaneous tissue: A case report and literature review

  • Authors:
    • Yaonan Zhang
    • Zongyang Qu
    • Fang Fang
  • View Affiliations

  • Published online on: September 27, 2016     https://doi.org/10.3892/ol.2016.5194
  • Pages: 3687-3694
  • Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Langerhans cell sarcoma (LCS) is a neoplastic proliferation of Langerhans cells with notably malignant cytological features. Reports of LCS are sparsely available in English literature; to the best of our knowledge, only 55 cases have been reported. The present study reports a case of LCS originating from subcutaneous tissue of the left knee in a 75‑year‑old man. The diagnosis of LCS was supported by the results of magnetic resonance imaging, histological and immunohistochemical studies. The tumor began to metastasize to inguinal lymph nodes and eventually involved multiple organs. Chemotherapy and radiotherapy were administered but were ineffective, and the patient died within 2 years of diagnosis. The present case should aid in expanding the currently available knowledge concerning LCS.
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November-2016
Volume 12 Issue 5

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Zhang Y, Qu Z and Fang F: Langerhans cell sarcoma originating from left knee subcutaneous tissue: A case report and literature review. Oncol Lett 12: 3687-3694, 2016.
APA
Zhang, Y., Qu, Z., & Fang, F. (2016). Langerhans cell sarcoma originating from left knee subcutaneous tissue: A case report and literature review. Oncology Letters, 12, 3687-3694. https://doi.org/10.3892/ol.2016.5194
MLA
Zhang, Y., Qu, Z., Fang, F."Langerhans cell sarcoma originating from left knee subcutaneous tissue: A case report and literature review". Oncology Letters 12.5 (2016): 3687-3694.
Chicago
Zhang, Y., Qu, Z., Fang, F."Langerhans cell sarcoma originating from left knee subcutaneous tissue: A case report and literature review". Oncology Letters 12, no. 5 (2016): 3687-3694. https://doi.org/10.3892/ol.2016.5194