Imaging findings of extraventricular choroid plexus papillomas: A study of 10 cases

Shi,Yuzhen; Li,Xiaoshuang; Chen,Xiao; Xu,Yiming; Bo,Genji; Zhou,Hao; Liu,Yongkang; Zhou,Guoxing; Wang,Zhongqiu

doi:10.3892/ol.2016.5552

Imaging findings of extraventricular choroid plexus papillomas: A study of 10 cases

Authors:
- Yuzhen Shi
- Xiaoshuang Li
- Xiao Chen
- Yiming Xu
- Genji Bo
- Hao Zhou
- Yongkang Liu
- Guoxing Zhou
- Zhongqiu Wang
View Affiliations

Affiliations: Department of Medical Imaging, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, Jiangsu 223300, P.R. China, Department of Radiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210029, P.R. China, Department of Radiology, East Hospital, Tongji University School of Medicine, Shanghai 200120, P.R. China
Published online on: December 30, 2016 https://doi.org/10.3892/ol.2016.5552
Pages: 1479-1485

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

Extraventricular choroid plexus papillomas (CPPs) are rare. In this study, we reveal the imaging findings of CPPs located in extraventricular sites. The imaging findings of 11 masses [10 masses on magnetic resonance imaging (MRI) and one mass on computed tomography (CT)] of extraventricular CPP in 10 patients were retrospectively observed. The mass site, size, contour, signal intensity, cystic or solid appearance, calcification, capsules, degree and pattern of enhancement, and hydrocephalus were evaluated based on CT or MRI. The misdiagnosis rate of CPPs in extraventricular sites was 80.0% (8/10). Solitary masses and multiple masses were observed in nine patients (90.0%, 9/10) and one patient (10%, 1/10), respectively. In addition to the typical imaging findings [a lobulated, cauliflower‑like or mulberry‑like mass that is homogeneous isointense or slightly hypointense on T1‑weighted imaging (T1WI) and heterogeneous isointense or slightly hyperintense on T2WI], four masses had round or oval contours and three had cystic components; abnormal signal intensity (mixed hyperintense signals on T1WI and T2WI or slightly hyperintense signals on T1WI or hypo‑/hyperintense on T2WI) and low or no enhancements were observed in three and six masses, respectively; absence of hydrocephalus and mild or local hydrocephalus were each observed in four subjects, respectively. Hemorrhage and psammomatous bodies and/or calcification were observed in four and three masses, respectively. In conclusion, in addition to the typical imaging findings, atypical imaging findings, including atypical contours, abnormal signal intensity, low enhancement and absence of hydrocephalus were also observed in extraventricular CPPs.

View Figures

View References

1	Khoddami M and Gholampour Shahaboddini R: Choroid plexus papilloma of the cerebellopontine angle. Arch Iran Med. 13:552–555. 2010.PubMed/NCBI
2	Wolff JE, Sajedi M, Brant R, Coppes MJ and Egeler RM: Choroid plexus tumours. Br J Cancer. 87:1086–1091. 2002. View Article : Google Scholar : PubMed/NCBI
3	Tan LA, Fontes RB and Byrne RW: Retrosigmoid approach for resection of an extraventricular choroid plexus papilloma in the cerebellopontine angle. Neurosurg Focus. 36(1): Suppl. 12014. View Article : Google Scholar
4	Shin JH, Lee HK, Jeong AK, Park SH, Choi CG and Suh DC: Choroid plexus papilloma in the posterior cranial fossa: MR, CT and angiographic findings. Clin Imaging. 25:154–162. 2001. View Article : Google Scholar : PubMed/NCBI
5	Menon G, Nair SN, Baldawa SS, Rao RB, Krishnakumar KP and Gopalakrishnan CV: Choroid plexus tumors: an institutional series of 25 patients. Neurol India. 58:429–435. 2010. View Article : Google Scholar : PubMed/NCBI
6	Girardot C, Boukobza M, Lamoureux JP, Sichez JP, Capelle L, Zouaoui A, Bencherif B and Metzger J: Choroid plexus papillomas of the posterior fossa in adults: MR imaging and gadolinium enhancement. Report of four cases and review of the literature. J Neuroradiol. 17:303–318. 1990.(In English and French). PubMed/NCBI
7	McEvoy AW, Harding BN, Phipps KP, Ellison DW, Elsmore AJ, Thompson D and Harkness W: Management of choroid plexus tumours in children: 20 years experience at a single neurosurgical centre. Pediatr Neurosurg. 32:192–199. 2000. View Article : Google Scholar : PubMed/NCBI
8	Borota O Casar, Jacobsen EA and Scheie D: Bilateral atypical choroid plexus papillomas in cerebellopontine angles mimicking neurofibromatosis 2. Acta Neuropathol. 111:500–502. 2006. View Article : Google Scholar : PubMed/NCBI
9	Mahta A, Kim RY and Kesari S: Fourth ventricular choroid plexus papilloma. Med Oncol. 29:1285–1286. 2012. View Article : Google Scholar : PubMed/NCBI
10	Bonneville F, Savatovsky J and Chiras J: Imaging of cerebellopontine angle lesions: an update. Part 2: Intra-axial lesions, skull base lesions that may invade the CPA region and non-enhancing extra-axial lesions. Eur Radiol. 17:2908–2920. 2007. View Article : Google Scholar : PubMed/NCBI
11	Coates TL, Hinshaw DB, Peckman N, Thompson JR, Hasso AN, Holshouser BA and Knierim DS: Pediatric choroid plexus neoplasms: MR, CT and pathologic correlation. Radiology. 173:81–88. 1989. View Article : Google Scholar : PubMed/NCBI
12	Sugiyama K and Kurisu K: Choroid plexus tumor-choroid plexus papilloma and choroid plexus carcinoma. Ryoikibetsu Shokogun Shirizu. 28:57–64. 2000.(In Japanese).
13	DeMarchi R, Al Khalidi H, Fazl M and Bilbao JM: Primary choroid plexus papilloma of the cauda equina. A case report. Can J Neurol Sci. 37:416–418. 2010. View Article : Google Scholar : PubMed/NCBI
14	Gelabert-Gonzalez M, Serramito-Garcia R, Arcos-Algaba A, Santin-Amo JM and Allut AG: Extraventricular choroid plexus papilloma. Rev Neurol. 48:559–560. 2009.(In Spanish). PubMed/NCBI
15	Stafrace S and Molloy J: Extraventricular choroid plexus papilloma in a neonate. Pediatr Radiol. 38:5932008. View Article : Google Scholar : PubMed/NCBI
16	Tena-Suck ML, Lopez-Gomez M, Salinas-Lara C, Arce-Arellano RI, Biol AS and Renbao-Bojorquez D: Psammomatous choroid plexus papilloma: three cases with atypical characteristics. Surg Neurol. 65:604–610. 2006. View Article : Google Scholar : PubMed/NCBI
17	Scholsem M, Scholtes F, Robe PA, Bianchi E, Kroonen J and Deprez M: Multifocal choroid plexus papilloma: a case report. Clin Neuropathol. 31:430–434. 2012. View Article : Google Scholar : PubMed/NCBI
18	McCall T, Binning M, Blumenthal DT and Jensen RL: Variations of disseminated choroid plexus papilloma: 2 case reports and a review of the literature. Surg Neurol. 66:62–67. 2006. View Article : Google Scholar : PubMed/NCBI
19	Jaiswal AK, Jaiswal S, Sahu RN, Das KB, Jain VK and Behari S: Choroid plexus papilloma in children: diagnostic and surgical considerations. J Pediatr Neurosci. 4:10–16. 2009. View Article : Google Scholar : PubMed/NCBI
20	Wyatt-Ashmead J, Kleinschmidt-DeMasters B, Mierau GW, Malkin D, Orsini E, McGavran L and Foreman NK: Choroid plexus carcinomas and rhabdoid tumors: phenotypic and genotypic overlap. Pediatr Dev Pathol. 4:545–549. 2001. View Article : Google Scholar : PubMed/NCBI
21	Barreto AS, Vassallo J and Lde S Queiroz: Papillomas and carcinomas of the choroid plexus: histological and immunohistochemical studies and comparison with normal fetal choroid plexus. Arq Neuropsiquiatr. 62:600–607. 2004. View Article : Google Scholar : PubMed/NCBI
22	Xiao A, Xu J, He X and You C: Extraventricular choroid plexus papilloma in the brainstem. J Neurosurg Pediatr. 12:247–250. 2013. View Article : Google Scholar : PubMed/NCBI
23	Talacchi A, De Micheli E, Lombardo C, Turazzi S and Bricolo A: Choroid plexus papilloma of the cerebellopontine angle: a twelve patient series. Surg Neurol. 51:621–629. 1999. View Article : Google Scholar : PubMed/NCBI
24	Shogan P, Banks KP and Brown S: AJR teaching file: intraventricular mass. Am J Roentgenol. 189:S55–S57. 2007. View Article : Google Scholar
25	Li S and Savolaine ER: Imaging of atypical choroid plexus papillomas. Clin Imaging. 20:85–90. 1996. View Article : Google Scholar : PubMed/NCBI
26	Luo B, Sun G, Zhang B, Liang K, Wen J and Fang K: Neuroradiological findings of intracranial schwannomas not arising from the stems of cranial nerves. Br J Radiol. 77:1016–1021. 2004. View Article : Google Scholar : PubMed/NCBI
27	Wilms G, Lammens M, Marchal G, Van Calenbergh F, Plets C, Van Fraeyenhoven L and Baert AL: Thickening of dura surrounding meningiomas: MR features. J Comput Assist Tomogr. 13:763–776. 1989. View Article : Google Scholar : PubMed/NCBI