Analysis of health-related quality of life in patients with brain tumors prior and subsequent to radiotherapy

  • Authors:
    • Claudia Bitterlich
    • Dirk Vordermark
  • View Affiliations

  • Published online on: June 6, 2017     https://doi.org/10.3892/ol.2017.6310
  • Pages: 1841-1846
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Abstract

Health-related quality of life (HRQOL) was evaluated for a patient cohort with benign or malignant brain tumors prior and subsequent to radiotherapy. The following inclusion criteria were applied: Sufficient compliance, understanding of patient information and the existence of a brain tumor without previous radiotherapy. Patients were asked to complete the European Organization for Research and Treatment of Cancer QLQ‑C30 and QLQ‑BN20 questionnaires at the following times: Prior to (t0) and subsequent to (t1) radiotherapy, and at 3 (t2), 6 (t3) and 12 (t4) months following treatment. In addition, at t1 the side effects were assessed according to the Common Terminology Criteria for Adverse Events. Generally, the global QOL, a standard term describing general QOL, improved slightly (t0=49; t4=65). At t1, a significant increase in fatigue, loss of appetite and alopecia was reported. During follow‑up, the symptoms experienced by the patients decreased, and the global QOL remained constant. The objectively recorded side effects of the therapy were comparable with the patient‑reported outcomes.
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August-2017
Volume 14 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Bitterlich C and Bitterlich C: Analysis of health-related quality of life in patients with brain tumors prior and subsequent to radiotherapy. Oncol Lett 14: 1841-1846, 2017
APA
Bitterlich, C., & Bitterlich, C. (2017). Analysis of health-related quality of life in patients with brain tumors prior and subsequent to radiotherapy. Oncology Letters, 14, 1841-1846. https://doi.org/10.3892/ol.2017.6310
MLA
Bitterlich, C., Vordermark, D."Analysis of health-related quality of life in patients with brain tumors prior and subsequent to radiotherapy". Oncology Letters 14.2 (2017): 1841-1846.
Chicago
Bitterlich, C., Vordermark, D."Analysis of health-related quality of life in patients with brain tumors prior and subsequent to radiotherapy". Oncology Letters 14, no. 2 (2017): 1841-1846. https://doi.org/10.3892/ol.2017.6310