Open Access

Diagnosing giant cell tumor of the bone using positron emission tomography/computed tomography: A retrospective study of 20 patients from a single center

  • Authors:
    • Aikeremujiang Muheremu
    • Yuan Ma
    • Zhen Huang
    • Huachao Shan
    • Yuan Li
    • Xiaohui Niu
  • View Affiliations

  • Published online on: June 14, 2017     https://doi.org/10.3892/ol.2017.6379
  • Pages: 1985-1988
  • Copyright: © Muheremu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The aim of the present study was to evaluate the sensitivity of positron emission tomography/computed tomography (PET/CT) in the diagnosis of giant cell tumor of the bone (GCTB) using the maximum standard uptake value (SUVmax), which indicates the metabolic rate of tissue. Patients diagnosed with pathologically confirmed GCTB between January 2006 and July 2015 were included in the study. Data from PET/CT scans and pathological and clinical reports for all patients were retrospectively reviewed. The SUVmax value from the PET/CT scan of each patient was retrieved and analyzed. A total of 20 patients [12 male and 8 female; age range, 12‑45 years; mean age ± standard deviation (SD), 33.5±15.7] with complete PET/CT data and a pathologically and clinically confirmed diagnosis were examined. The SUVmax of GCTB was between 1.8 and 18.6, with a mean ± SD of 9.2±3.8. Although GCTB is not considered to be a malignant lesion, PET/CT scans of the tumors reveal high‑grade malignant osseous sarcomas. It is, therefore, important not to mistake such lesions for osteosarcomas or metastatic malignancies of the bone.
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August-2017
Volume 14 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Muheremu A, Ma Y, Huang Z, Shan H, Li Y and Niu X: Diagnosing giant cell tumor of the bone using positron emission tomography/computed tomography: A retrospective study of 20 patients from a single center. Oncol Lett 14: 1985-1988, 2017
APA
Muheremu, A., Ma, Y., Huang, Z., Shan, H., Li, Y., & Niu, X. (2017). Diagnosing giant cell tumor of the bone using positron emission tomography/computed tomography: A retrospective study of 20 patients from a single center. Oncology Letters, 14, 1985-1988. https://doi.org/10.3892/ol.2017.6379
MLA
Muheremu, A., Ma, Y., Huang, Z., Shan, H., Li, Y., Niu, X."Diagnosing giant cell tumor of the bone using positron emission tomography/computed tomography: A retrospective study of 20 patients from a single center". Oncology Letters 14.2 (2017): 1985-1988.
Chicago
Muheremu, A., Ma, Y., Huang, Z., Shan, H., Li, Y., Niu, X."Diagnosing giant cell tumor of the bone using positron emission tomography/computed tomography: A retrospective study of 20 patients from a single center". Oncology Letters 14, no. 2 (2017): 1985-1988. https://doi.org/10.3892/ol.2017.6379