Long non-coding RNAs as novel biomarkers for breast cancer invasion and metastasis (Review)

  • Authors:
    • Kaijiong Zhang
    • Zhenglian Luo
    • Yi Zhang
    • Xiaoyu Song
    • Li Zhang
    • Lichun Wu
    • Jinbo Liu
  • View Affiliations

  • Published online on: June 22, 2017     https://doi.org/10.3892/ol.2017.6462
  • Pages: 1895-1904
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Breast cancer (BC) is now the most common malignancy worldwide, with high prevalence and lethality among women. Invasion and metastasis are the major reasons for breast cancer‑associated mortality. However, the underlying mechanism of invasion and metastasis has not been entirely elucidated. Long non‑coding RNAs (lncRNAs) are a large class of non‑coding transcripts that are >200 bases in length and cannot encode proteins. Evidence has indicated that lncRNAs regulate gene expression at the levels of epigenetic modification, transcription and post‑transcription. In addition, they are involved in diverse tumor biological processes, including cell proliferation, apoptosis, invasion, metastasis and angiogenesis. The present review focuses on the recent progress of lncRNAs in breast cancer invasion and metastasis, aiming to provide novel strategies for the clinical prevention, diagnosis and treatment of breast cancer.
View References

Related Articles

Journal Cover

August-2017
Volume 14 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Zhang K, Luo Z, Zhang Y, Song X, Zhang L, Wu L and Liu J: Long non-coding RNAs as novel biomarkers for breast cancer invasion and metastasis (Review). Oncol Lett 14: 1895-1904, 2017
APA
Zhang, K., Luo, Z., Zhang, Y., Song, X., Zhang, L., Wu, L., & Liu, J. (2017). Long non-coding RNAs as novel biomarkers for breast cancer invasion and metastasis (Review). Oncology Letters, 14, 1895-1904. https://doi.org/10.3892/ol.2017.6462
MLA
Zhang, K., Luo, Z., Zhang, Y., Song, X., Zhang, L., Wu, L., Liu, J."Long non-coding RNAs as novel biomarkers for breast cancer invasion and metastasis (Review)". Oncology Letters 14.2 (2017): 1895-1904.
Chicago
Zhang, K., Luo, Z., Zhang, Y., Song, X., Zhang, L., Wu, L., Liu, J."Long non-coding RNAs as novel biomarkers for breast cancer invasion and metastasis (Review)". Oncology Letters 14, no. 2 (2017): 1895-1904. https://doi.org/10.3892/ol.2017.6462