Implementation of diffusion-weighted magnetic resonance imaging in target delineation of central lung cancer accompanied 
with atelectasis in precision radiotherapy

Zhang,Xinli; Fu,Zheng; Gong,Guanzhong; Wei,Hong; Duan,Jinghao; Chen,Zhaoqiu; Chen,Xiangming; Wang,Ruozheng; Yin,Yong

doi:10.3892/ol.2017.6479

Implementation of diffusion-weighted magnetic resonance imaging in target delineation of central lung cancer accompanied with atelectasis in precision radiotherapy

Authors:
- Xinli Zhang
- Zheng Fu
- Guanzhong Gong
- Hong Wei
- Jinghao Duan
- Zhaoqiu Chen
- Xiangming Chen
- Ruozheng Wang
- Yong Yin
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Affiliations: Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong University, Jinan, Shandong 250117, P.R. China, Department of Medical Oncology, Tai'an City Central Hospital, Tai'an, Shandong 271000, P.R. China, Department of Radiation Oncology, Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830011, P.R. China
Published online on: June 23, 2017 https://doi.org/10.3892/ol.2017.6479
Pages: 2677-2682
Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Radiotherapy, particularly the target delineation of cancer based on scanned images, plays a key role in the planning of cancer treatment. Recently, diffusion‑weighted magnetic resonance imaging (DW‑MRI) has emerged as a prospective superior procedure compared with intensified computed tomography (CT) and positron emission tomography (PET) in the target delineation of cancer. However, the implication of DW‑MRI in lung cancer, the leading cause of cancer‑associated mortality worldwide, has not been extensively evaluated. In the present study, the gross target volumes of lung cancer masses delineated using the DW‑MRI, CT and PET procedures were compared in a pairwise manner in a group of 27 lung cancer patients accompanied with atelectasis of various levels. The data showed that compared with CT and PET procedures, DW‑MRI has a more precise delineation of lung cancer while exhibiting higher reproducibility. Together with the fact that it is non‑invasive and cost‑effective, these data demonstrate the great application potential of the DW‑MRI procedure in cancer precision radiotherapy.

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