Primary non-Hodgkin's lymphoma of the vagina: A case report

Wang,Feng; Jing,Xuquan; Liu,Bo; Meng,Xue; Sun,Xindong; Gao,Yongsheng; Wang,Linlin; Fu,Zheng

doi:10.3892/ol.2018.7805

Primary non-Hodgkin's lymphoma of the vagina: A case report

Authors:
- Feng Wang
- Xuquan Jing
- Bo Liu
- Xue Meng
- Xindong Sun
- Yongsheng Gao
- Linlin Wang
- Zheng Fu
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Affiliations: School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan, Shandong 250200, P.R. China, Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Jinan, Shandong 250117, P.R. China, Department of Medical Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Jinan, Shandong 250117, P.R. China, Department of Pathology, Shandong Cancer Hospital Affiliated to Shandong University, Jinan, Shandong 250117, P.R. China, Department of Computed Tomography, Shandong Cancer Hospital Affiliated to Shandong University, Jinan, Shandong 250117, P.R. China
Published online on: January 16, 2018 https://doi.org/10.3892/ol.2018.7805
Pages: 3504-3507
Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Primary non-Hodgkin's lymphoma (NHL) of the vagina is uncommon. The present case study reports the case of a 54-year-old female with a palpable mass between the rectum and vagina. The patient presented with symptoms consistent with vaginal cancer but lacked any of the ‘B’ symptoms often associated with systemic lymphoma, including fever, weight loss, night sweats and fatigue. The mass was resected under anesthesia. Immunohistochemistry and biopsy conﬁrmed diffuse large B‑cell NHL (DLBCL). Following surgery, six cycles of chemotherapy with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone were administered. Subsequently, a vertebral body metastasis was observed using a computed tomography scan and whole‑body bone imaging. The patient received palliative radiation for the vertebral body metastasis. Additionally, the available literature was reviewed in order to further characterize this rare disease.

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