Computed tomography imaging features of benign ovarian Brenner tumors

Zhao,Yuying; Mao,Xinfeng; Yao,Lidi; Shen,Jian

doi:10.3892/ol.2018.8766

Computed tomography imaging features of benign ovarian Brenner tumors

Authors:
- Yuying Zhao
- Xinfeng Mao
- Lidi Yao
- Jian Shen
View Affiliations

Affiliations: Department of Radiology, Huzhou Central Hospital, Huzhou, Zhejiang 313003, P.R. China
Published online on: May 22, 2018 https://doi.org/10.3892/ol.2018.8766
Pages: 1141-1146

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

The present study aimed to describe the computed tomography (CT) imaging features of ovarian Brenner tumor for diagnostic accuracy and disease understanding. The CT imaging features of 9 cases of ovarian Brenner tumor confirmed by surgery and pathology were retrospectively analyzed and compared. Of the 9 cases of ovarian Brenner tumor, 3 were right located and 6 were left located with clear borders; 7 with round or oval shapes, while 2 were with irregular and lobulated morphology; 5 solid lesions presented with multiple scattered calcification shadows inside with moderate enhancement, while 3 cystic lesions were presented with mixed solid and cystic composition, and significant enhancement was identified in the solid component, but not in the cystic component. Furthermore, papillary projections inside and mild nodular enhancement were observed in one case of cystic lesion. The pathological analysis demonstrated that an epithelium nest composed the tumors with urothelial like cells and fibrous matrix. Of the 9 cases, 5 epithelial nests exhibited adeno‑like cystic lumen without cell mitosis phase. All cases were diagnosed with benign ovarian Brenner tumor. Specific CT imaging features of ovarian Brenner tumor can be identified and pathological examinations are required for diagnosis confirmation.

View Figures

View References

1	Green GE, Mortele KJ, Glickman JN and Benson CB: Brenner tumors of the ovary: Sonographic and computed tomographic imaging features. J Ultrasound Med. 25:1245–1251. 2006. View Article : Google Scholar : PubMed/NCBI
2	Buy J, Ghossain M, Sciot C, Bazot M, Guinet C, Prevot S, Hugol D, Laromiguiere M, Truc J, Poitout P, et al: Epithelial tumors of the ovary: CT findings and correlation with US. Radiology. 178:811–818. 1991. View Article : Google Scholar : PubMed/NCBI
3	Jung SE, Lee JM, Rha SE, Byun JY, Jung JI and Hahn ST: CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. Radiographics. 22:1305–1325. 2002. View Article : Google Scholar : PubMed/NCBI
4	Dierickx I, Valentin L, van Holsbeke C, Jacomen G, Lissoni AA, Licameli A, Testa A, Bourne T and Timmerman D: Imaging in gynecological disease (7): Clinical and ultrasound features of Brenner tumors of the ovary. Ultrasound Obstet Gynecol. 40:706–713. 2012. View Article : Google Scholar : PubMed/NCBI
5	Balasa RW, Adcock LL, Prem KA and Dehner LP: The Brenner tumor: A clinicopathologic review. Obstet Gynecol. 50:120–121. 1977.PubMed/NCBI
6	Ordóñez NG and MacKay B: Brenner tumor of the ovary: A comparative immunohistochemical and ultrastructural study with transitional cell carcinoma of the bladder. Ultrastruct Pathol. 24:157–167. 2000. View Article : Google Scholar : PubMed/NCBI
7	Silverberg SG: Brenner tumor of the ovary. A clinicopathologic study of 60 tumors in 54 women. Cancer. 28:588–596. 1971.
8	van der Westhuizen A and Tiltman AJ: Brenner tumours-a clinicopathological study. S Afr Med J. 73:98–101. 1988.PubMed/NCBI
9	Cuatrecasas M, Catasus L, Palacios J and Prat J: Transitional cell tumors of the ovary: A comparative clinicopathologic, immunohistochemical, and molecular genetic analysis of Brenner tumors and transitional cell carcinomas. Am J Surg Pathol. 33:556–567. 2009. View Article : Google Scholar : PubMed/NCBI
10	Kurman RJ: Blaustein's pathology of the female genital tract. Springer Science & Business Media; 2013
11	Scully RE, Bonfiglio TA, Kurman RJ, Silverberg SG and Wilkinson E: Histological typing of female genital tract tumours. Springer Science & Business Media; 2012
12	Wang XY, Dai JR, Zhu Z, Zhao YF and Zhou CW: CT features of ovarian Brenner tumor and a report of 9 cases. Zhonghua Zhong Liu Za Zhi. 32:359–362. 2010.(In Chinese). PubMed/NCBI
13	Levine D, Brown DL, Andreotti RF, Benacerraf B, Benson CB, Brewster WR, Coleman B, DePriest P, Doubilet PM, Goldstein SR, et al: Management of asymptomatic ovarian and other adnexal cysts imaged at US: Society of radiologists in ultrasound consensus conference statement 1. Radiology. 256:943–954. 2010. View Article : Google Scholar : PubMed/NCBI
14	Moon WJ, Koh BH, Kim SK, Kim YS, Rhim HC, Cho OK, Hahm CK, Byun JY, Cho KS and Kim SH: Brenner tumor of the ovary: CT and MR findings. J Comput Assisted Tomogr. 24:72–76. 2000. View Article : Google Scholar
15	Imaoka I, Wada A, Kaji Y, Hayashi T, Hayashi M, Matsuo M and Sugimura K: Developing an MR imaging strategy for diagnosis of ovarian masses. Radiographics. 26:1431–1448. 2006. View Article : Google Scholar : PubMed/NCBI
16	Bristow R and Montz F: Leiomyomatosis peritonealis disseminata and ovarian Brenner tumor associated with tamoxifen use. Int J Gynecol Cancer. 11:312–315. 2001. View Article : Google Scholar : PubMed/NCBI
17	Boyle KJ and Torrealday S: Benign gynecologic conditions. Surg Clin North Am. 88:245–264. 2008. View Article : Google Scholar : PubMed/NCBI