Open Access

Effect of the degree of gastric filling on the measured thickness of advanced gastric cancer by computed tomography

  • Authors:
    • Li Yang
    • Yong Li
    • Tao Zhou
    • Gaofeng Shi
    • Jiangyang Pan
    • Jing Liu
    • Guangda Wang
  • View Affiliations

  • Published online on: June 5, 2018     https://doi.org/10.3892/ol.2018.8907
  • Pages: 2335-2343
  • Copyright: © Yang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Imaging of gastric cancer thickness is closely associated with the depth of tumor invasion, which provides guidance for clinical staging and assists the evaluation of the effects of adjuvant therapy. However, it is unclear whether the measurement of thickness is affected by the degree of gastric filling, and its accuracy and reliability are under‑reported. The present study aimed to investigate the influence of the degree of gastric filling on the measurement of gastric cancer thickness. A total of 38 patients with advanced gastric cancer who underwent enhanced abdominal computed tomography (CT) scanning at the Department of CT and MR in The Fourth Hospital of Hebei Medical University (Shijiazhuang, China) between July and September 2016 were recruited, consisting of 21 newly diagnosed cases and 17 follow‑up cases following non‑surgical treatments. Plain scanning (prior to filling) and enhanced scanning in venous phase (following filling) were performed. Axial CT images prior to and following filling of the normal part of gastric wall and the lesions were compared. The same procedure was repeated on these participants 1 month later by the same radiologist, and the results were compared with those obtained previously. Normal gastric wall thickness prior to and following gastric filling was significantly different (all P<0.001) with the most substantial changes observed at the greater curvature. Lesion thickness prior to and following filling was similar in newly diagnosed patients, but significantly different in patients for re‑examination (P<0.05). The two thickness measurements in the same patients were consistent. The measured thickness of gastric cancer in newly diagnosed patients was relatively stable, and could be used as an indicator in baseline CT examination. Maintaining a similar degree of gastric filling during re‑examination could aid the accurate evaluation of treatment efficacy.
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August-2018
Volume 16 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Yang L, Li Y, Zhou T, Shi G, Pan J, Liu J and Wang G: Effect of the degree of gastric filling on the measured thickness of advanced gastric cancer by computed tomography. Oncol Lett 16: 2335-2343, 2018.
APA
Yang, L., Li, Y., Zhou, T., Shi, G., Pan, J., Liu, J., & Wang, G. (2018). Effect of the degree of gastric filling on the measured thickness of advanced gastric cancer by computed tomography. Oncology Letters, 16, 2335-2343. https://doi.org/10.3892/ol.2018.8907
MLA
Yang, L., Li, Y., Zhou, T., Shi, G., Pan, J., Liu, J., Wang, G."Effect of the degree of gastric filling on the measured thickness of advanced gastric cancer by computed tomography". Oncology Letters 16.2 (2018): 2335-2343.
Chicago
Yang, L., Li, Y., Zhou, T., Shi, G., Pan, J., Liu, J., Wang, G."Effect of the degree of gastric filling on the measured thickness of advanced gastric cancer by computed tomography". Oncology Letters 16, no. 2 (2018): 2335-2343. https://doi.org/10.3892/ol.2018.8907