Lymphoepithelioma‑like gastric carcinoma treated with partial gastrectomy: Two case reports

Cao,Huihua; Xie,Jun; Qian,Yongxiang; Wu,Yugang; Tang,Zhaoqing

doi:10.3892/ol.2019.10368

Lymphoepithelioma‑like gastric carcinoma treated with partial gastrectomy: Two case reports

Authors:
- Huihua Cao
- Jun Xie
- Yongxiang Qian
- Yugang Wu
- Zhaoqing Tang
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Affiliations: Department of General Surgery, The Third Affiliated Hospital of Soochow University and The First People's Hospital of Changzhou, Changzhou, Jiangsu 213000, P.R. China, Department of Pathology, The Third Affiliated Hospital of Soochow University and The First People's Hospital of Changzhou, Changzhou, Jiangsu 213000, P.R. China, Department of Cardiothoracic Surgery, The Third Affiliated Hospital of Soochow University and The First People's Hospital of Changzhou, Changzhou, Jiangsu 213000, P.R. China, Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China
Published online on: May 17, 2019 https://doi.org/10.3892/ol.2019.10368
Pages: 545-552
Copyright: © Cao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Lymphoepithelioma‑like gastric carcinoma (LELGC) is a rare type of gastric cancer characterized by intense lymphocytic infiltration of the stroma. LELGC is associated with Epstein‑Barr virus infection and has a favorable prognosis compared with other types of gastric carcinoma. The clinical symptoms of LELGC are usually similar to those of conventional gastric carcinoma. The diagnosis of LELGC is established based on pathological, histological and immunohistochemical findings. The present report describes the cases of two patients with LELGC who underwent esophagogastroduodenoscopy and computed tomography scans prior to surgery. The two patients accepted surgical treatment, and postoperative pathological and immunohistochemical analyses confirmed LELGC. Neither patient experienced local recurrence or distant metastasis during the postoperative period.

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