1
|
Global Burden of Disease Cancer
Collaboration, . Fitzmaurice C, Allen C, Barber RM, Barregard L,
Bhutta ZA, Brenner H, Dicker DJ, Chimed-Orchir O, Dandona R, et al:
Global, regional, and national cancer incidence, mortality, years
of life lost, years lived with disability, and disability-adjusted
life-years for 32 cancer groups, 1990 to 2015: A systematic
analysis for the global burden of disease study. JAMA Oncol.
3:524–548. 2017. View Article : Google Scholar : PubMed/NCBI
|
2
|
Chen W, Zheng R, Baade PD, Zhang S, Zeng
H, Bray F, Jemal A, Yu XQ and He J: Cancer statistics in China,
2015. CA Cancer J Clin. 66:115–132. 2016. View Article : Google Scholar : PubMed/NCBI
|
3
|
NCCN, . NCCN Clinical Practice Guidelines
in Oncology (NCCN Guidelines®): Hepatobiliary Cancers
(Version 3.2018). 2018.
|
4
|
Zhang JF, Shu ZJ, Xie CY, Li Q, Jin XH, Gu
W, Jiang FJ and Ling CQ: Prognosis of unresectable hepatocellular
carcinoma: Comparison of seven staging systems (TNM, Okuda, BCLC,
CLIP, CUPI, JIS, CIS) in a Chinese cohort. PLoS One. 9:e881822014.
View Article : Google Scholar : PubMed/NCBI
|
5
|
Chen ZH, Hong YF, Lin J, Li X, Wu DH, Wen
JY, Chen J, Ruan DY, Lin Q, Dong M, et al: Validation and ranking
of seven staging systems of hepatocellular carcinoma. Oncol Lett.
14:705–714. 2017. View Article : Google Scholar : PubMed/NCBI
|
6
|
Liu PH, Hsu CY, Hsia CY, Lee YH, Su CW,
Huang YH, Lee FY, Lin HC and Huo TI: Prognosis of hepatocellular
carcinoma: Assessment of eleven staging systems. J Hepatol.
64:601–608. 2016. View Article : Google Scholar : PubMed/NCBI
|
7
|
Sherman M: Staging for hepatocellular
carcinoma: Complex and confusing. Gastroenterology. 146:1599–1602.
2014. View Article : Google Scholar : PubMed/NCBI
|
8
|
Ahmed Mohammed HF and Roberts LR: Should
AFP (or any biomarkers) be used for HCC surveillance? Curr Hepatol
Rep. 16:137–145. 2017. View Article : Google Scholar : PubMed/NCBI
|
9
|
Zhou L, Rui JA, Wang SB, Chen SG and Qu Q:
Carbohydrate antigen 19-9 increases the predictive efficiency of
α-fetoprotein for prognosis of resected hepatocellular carcinoma.
Am Surg. 84:80–85. 2018.PubMed/NCBI
|
10
|
Guo S, Ran H, Xiao D, Huang H, Mi L, Wang
X, Chen L, Li D, Zhang S, Han Q, et al: NT5DC2 promotes
tumorigenicity of glioma stem-like cells by upregulating fyn.
Cancer Lett. 454:98–107. 2019. View Article : Google Scholar : PubMed/NCBI
|
11
|
Li KS, Zhu XD, Liu HD, Zhang SZ, Li XL,
Xiao N, Liu XF, Xu B, Lei M, Zhang YY, et al: NT5DC2 promotes tumor
cell proliferation by stabilizing EGFR in hepatocellular carcinoma.
Cell Death Dis. 11:3352020. View Article : Google Scholar : PubMed/NCBI
|
12
|
van Hulzen KJE, Scholz CJ, Franke B, Ripke
S, Klein M, McQuillin A, Sonuga-Barke EJ; PGC ADHD Working Group, ;
Kelsoe JR, Landén M, et al: Genetic overlap between
attention-deficit/hyperactivity disorder and bipolar disorder:
evidence from genome-wide association study meta-analysis. Biol
Psychiatry. 82:634–641. 2017. View Article : Google Scholar : PubMed/NCBI
|
13
|
Zayats T, Jacobsen KK, Kleppe R, Jacob CP,
Kittel-Schneider S, Ribasés M, Ramos-Quiroga JA, Richarte V, Casas
M, Mota NR, et al: Exome chip analyses in adult attention deficit
hyperactivity disorder. Transl Psychiatry. 6:e9232016. View Article : Google Scholar : PubMed/NCBI
|
14
|
Prados J, Stenz L, Courtet P, Prada P,
Nicastro R, Adouan W, Guillaume S, Olié E, Aubry JM, Dayer A and
Perroud N: Borderline personality disorder and childhood
maltreatment: A genome-wide methylation analysis. Genes Brain
Behav. 14:177–188. 2015. View Article : Google Scholar : PubMed/NCBI
|
15
|
Colaprico A, Silva TC, Olsen C, Garofano
L, Cava C, Garolini D, Sabedot TS, Malta TM, Pagnotta SM,
Castiglioni I, et al: TCGAbiolinks: An R/Bioconductor package for
integrative analysis of TCGA data. Nucleic Acids Res. 44:e712016.
View Article : Google Scholar : PubMed/NCBI
|
16
|
Forner A, Reig M and Bruix J:
Hepatocellular carcinoma. Lancet. 391:1301–1314. 2018. View Article : Google Scholar : PubMed/NCBI
|
17
|
Amin M, Edge S, Greene FL, Schilsky RL,
Byrd DR, Gaspar LE, Washington MK, Gershenwald JE, Compton CC and
Hess KR: AJCC cancer staging manual. 8th. Springer; New York, NY:
2017, View Article : Google Scholar
|
18
|
Zhou L, Rui JA, Zhou WX, Wang SB, Chen SG
and Qu Q: Edmondson-Steiner grade: A crucial predictor of
recurrence and survival in hepatocellular carcinoma without
microvascular invasio. Pathol Res Pract. 213:824–830. 2017.
View Article : Google Scholar : PubMed/NCBI
|
19
|
Jiang Y, Sun A, Zhao Y, Ying W, Sun H,
Yang X, Xing B, Sun W, Ren L, Hu B, et al: Proteomics identifies
new therapeutic targets of early-stage hepatocellular carcinoma.
Nature. 567:257–261. 2019. View Article : Google Scholar : PubMed/NCBI
|
20
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
21
|
R Core Team, . R: A language and
environment for statistical computing. R Foundation for Statistical
Computing; Vienna, Austria: 2018
|
22
|
Mootha VK, Lindgren CM, Eriksson KF,
Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E,
Ridderstråle M, Laurila E, et al: PGC-1alpha-responsive genes
involved in oxidative phosphorylation are coordinately
downregulated in human diabetes. Nat Genet. 34:267–273. 2003.
View Article : Google Scholar : PubMed/NCBI
|
23
|
Subramanian A, Tamayo P, Mootha VK,
Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub
TR, Lander ES and Mesirov JP: Gene set enrichment analysis: A
knowledge-based approach for interpreting genome-wide expression
profiles. Proc Natl Acad Sci USA. 102:15545–15550. 2005. View Article : Google Scholar : PubMed/NCBI
|
24
|
Kim D, Langmead B and Salzberg SL: HISAT:
A fast spliced aligner with low memory requirements. Nat Methods.
12:357–360. 2015. View Article : Google Scholar : PubMed/NCBI
|
25
|
Liao Y, Smyth GK and Shi W: featureCounts:
An efficient general purpose program for assigning sequence reads
to genomic features. Bioinformatics. 30:923–930. 2014. View Article : Google Scholar : PubMed/NCBI
|
26
|
Love MI, Huber W and Anders S: Moderated
estimation of fold change and dispersion for RNA-seq data with
DESeq2. Genome Biol. 15:5502014. View Article : Google Scholar : PubMed/NCBI
|
27
|
Sia D, Villanueva A, Friedman SL and
Llovet JM: Liver cancer cell of origin, molecular class, and
effects on patient prognosis. Gastroenterology. 152:745–761. 2017.
View Article : Google Scholar : PubMed/NCBI
|
28
|
Yang SL, Liu LP, Yang S, Liu L, Ren JW,
Fang X, Chen GG and Lai PB: Preoperative serum α-fetoprotein and
prognosis after hepatectomy for hepatocellular carcinoma. Br J
Surg. 103:716–724. 2016. View Article : Google Scholar : PubMed/NCBI
|
29
|
Liu J, Xia Y, Shi L, Li X, Wu L and Yan Z:
Elevated serum carcinoembryonic antigen is associated with a worse
survival outcome of patients after liver resection for
hepatocellular carcinoma: A propensity score matching analysis. J
Gastrointest Surg. 20:2063–2073. 2016. View Article : Google Scholar : PubMed/NCBI
|
30
|
Hsu CC, Goyal A, Iuga A, Krishnamoorthy S,
Lee V, Verna EC, Wang S, Chen FN, Rodriguez R, Emond J, et al:
Elevated CA19-9 is associated with increased mortality in a
prospective cohort of hepatocellular carcinoma patients. Clin
Transl Gastroenterol. 6:e742015. View Article : Google Scholar : PubMed/NCBI
|
31
|
Suryavanshi M, Mehta A, Jaipuria J, Kumar
D, Vishwakarma G, Panigrahi MK, Verma H, Saifi M, Sharma S, Tandon
S, et al: Clinical utility of RT-PCR in assessing HER 2 gene
expression versus traditional IHC and FISH in breast cancer
patients. Breast Cancer. 25:416–430. 2018. View Article : Google Scholar : PubMed/NCBI
|
32
|
Zeng H, Zheng R, Guo Y, Zhang S, Zou X,
Wang N, Zhang L, Tang J, Chen J, Wei K, et al: Cancer survival in
China, 2003–2005: A population-based study. Int J Cancer.
136:1921–1930. 2015. View Article : Google Scholar : PubMed/NCBI
|
33
|
Tabrizian P, Jibara G, Shrager B, Schwartz
M and Roayaie S: Recurrence of hepatocellular cancer after
resection: Patterns, treatments, and prognosis. Ann Surg.
261:947–955. 2015. View Article : Google Scholar : PubMed/NCBI
|
34
|
Ma X, Gu J, Wang K, Zhang X, Bai J, Zhang
J, Liu C, Qiu Q and Qu K: Identification of a molecular subtyping
system associated with the prognosis of Asian hepatocellular
carcinoma patients receiving liver resection. Sci Rep. 9:70732019.
View Article : Google Scholar : PubMed/NCBI
|
35
|
Cao J, Wang P, Chen J and He X: PIGU
overexpression adds value to TNM staging in the prognostic
stratification of patients with hepatocellular carcinoma. Hum
Pathol. 83:90–99. 2019. View Article : Google Scholar : PubMed/NCBI
|
36
|
Liu C, Xiao GQ, Yan LN, Li B, Jiang L, Wen
TF, Wang WT, Xu MQ and Yang JY: Value of α-fetoprotein in
association with clinicopathological features of hepatocellular
carcinoma. World J Gastroenterol. 19:1811–1819. 2013. View Article : Google Scholar : PubMed/NCBI
|
37
|
Kamarajah SK, Frankel TL, Sonnenday C, Cho
CS and Nathan H: Critical evaluation of the American joint
commission on cancer (AJCC) 8th edition staging system for patients
with hepatocellular carcinoma (HCC): A surveillance, epidemiology,
end results (SEER) analysis. J Surg Oncol. 117:644–650. 2018.
View Article : Google Scholar : PubMed/NCBI
|
38
|
Ren B, Cam H, Takahashi Y, Volkert T,
Terragni J, Young RA and Dynlacht BD: E2F integrates cell cycle
progression with DNA repair, replication, and G(2)/M checkpoints.
Genes Dev. 16:245–256. 2002. View Article : Google Scholar : PubMed/NCBI
|
39
|
Kent LN and Leone G: The broken cycle: E2F
dysfunction in cancer. Nat Rev Cancer. 19:326–338. 2019. View Article : Google Scholar : PubMed/NCBI
|
40
|
Kent LN, Rakijas JB, Pandit SK, Westendorp
B, Chen HZ, Huntington JT, Tang X, Bae S, Srivastava A, Senapati S,
et al: E2f8 mediates tumor suppression in postnatal liver
development. J Clin Invest. 126:2955–2969. 2016. View Article : Google Scholar : PubMed/NCBI
|
41
|
Kent LN, Bae S, Tsai SY, Tang X,
Srivastava A, Koivisto C, Martin CK, Ridolfi E, Miller GC, Zorko
SM, et al: Dosage-dependent copy number gains in E2f1 and E2f3
drive hepatocellular carcinoma. J Clin Invest. 127:830–842. 2017.
View Article : Google Scholar : PubMed/NCBI
|
42
|
Giannelli G, Koudelkova P, Dituri F and
Mikulits W: Role of epithelial to mesenchymal transition in
hepatocellular carcinoma. J Hepatol. 65:798–808. 2016. View Article : Google Scholar : PubMed/NCBI
|
43
|
Malfettone A, Soukupova J, Bertran E,
Crosas-Molist E, Lastra R, Fernando J, Koudelkova P, Rani B, Fabra
Á, Serrano T, et al: Transforming growth factor-β-induced
plasticity causes a migratory stemness phenotype in hepatocellular
carcinoma. Cancer Lett. 392:39–50. 2017. View Article : Google Scholar : PubMed/NCBI
|
44
|
de Martel C, Maucort-Boulch D, Plummer M
and Franceschi S: World-wide relative contribution of hepatitis B
and C viruses in hepatocellular carcinoma. Hepatology.
62:1190–1200. 2015. View Article : Google Scholar : PubMed/NCBI
|
45
|
Wang T, Hsieh ET, Henry P, Hanna W,
Streutker CJ and Grin A: Matched biopsy and resection specimens of
gastric and gastroesophageal adenocarcinoma show high concordance
in HER2 status. Hum Pathol. 45:970–975. 2014. View Article : Google Scholar : PubMed/NCBI
|
46
|
Wang H, Agulnik J, Kasymjanova G, Wang A,
Jiménez P, Cohen V, Small D, Pepe C, Sakr L, Fiset PO, et al:
Cytology cell blocks are suitable for immunohistochemical testing
for PD-L1 in lung cancer. Ann Oncol. 29:1417–1422. 2018. View Article : Google Scholar : PubMed/NCBI
|