1
|
Liu SL, Cao SG, Li Y, Sun B, Chen D, Wang
DS and Zhou YB: Pancreatic stellate cells facilitate pancreatic
cancer cell viability and invasion. Oncol Lett. 17:2057–2062.
2019.PubMed/NCBI
|
2
|
Xiao M, Li T, Ji Y, Jiang F, Ni W, Zhu J,
Bao B, Lu C and Ni R: S100A11 promotes human pancreatic cancer
PANC-1 cell proliferation and is involved in the PI3K/AKT signaling
pathway. Oncol Lett. 15:175–182. 2018.PubMed/NCBI
|
3
|
Tajima H, Makino I, Ohbatake Y, Nakanuma
S, Hayashi H, Nakagawara H, Miyashita T, Takamura H and Ohta T:
Neoadjuvant chemotherapy for pancreatic cancer: Effects on cancer
tissue and novel perspectives. Oncol Lett. 13:3975–3981. 2017.
View Article : Google Scholar : PubMed/NCBI
|
4
|
Buwenge M, Cilla S, Cammelli S, Macchia G,
Arcelli A, Farina E, Frakulli R, Panni V, Wondemagegnhu T, Uddin
AFMK, et al: Feasibility of 2D-conformal radiotherapy for
pancreatic carcinoma. Oncol Lett. 16:5939–5945. 2018.PubMed/NCBI
|
5
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2019. CA Cancer J Clin. 69:7–34. 2019. View Article : Google Scholar : PubMed/NCBI
|
6
|
Chiou SH, Risca VI, Wang GX, Yang D,
Gruner BM, Kathiria AS, Ma RK, Vaka D, Chu P, Kozak M, et al:
BLIMP1 induces transient metastatic heterogeneity in pancreatic
cancer. Cancer Discov. 7:1184–1199. 2017. View Article : Google Scholar : PubMed/NCBI
|
7
|
Yokoyama N and Malbon CC: Dishevelled-2
docks and activates Src in a Wnt-dependent manner. J Cell Sci.
122:4439–4451. 2009. View Article : Google Scholar : PubMed/NCBI
|
8
|
Zhang H, Zhang H, Zhang Y, Ng SS, Ren F,
Wang Y, Duan Y, Chen L, Zhai Y, Guo Q and Chang Z: Dishevelled-DEP
domain interacting protein (DDIP) inhibits Wnt signaling by
promoting TCF4 degradation and disrupting the TCF4/beta-catenin
complex. Cell Signal. 22:1753–1760. 2010. View Article : Google Scholar : PubMed/NCBI
|
9
|
Gao C and Chen YG: Dishevelled: The hub of
Wnt signaling. Cell Signal. 22:717–727. 2010. View Article : Google Scholar : PubMed/NCBI
|
10
|
Yang Y, Jiao L, Hou J, Xu C, Wang L, Yu Y,
Li Y, Yang C, Wang X and Sun Y: Dishevelled-2 silencing reduces
androgen-dependent prostate tumor cell proliferation and migration
and expression of Wnt-3a and matrix metalloproteinases. Mol Biol
Rep. 40:4241–4250. 2013. View Article : Google Scholar : PubMed/NCBI
|
11
|
Zhang C, Li C, Chen X, Zhou Y, Yin B, Ni
R, Zhang Y and Liu J: Overexpression of dishevelled 2 is involved
in tumor metastasis and is associated with poor prognosis in
hepatocellular carcinoma. Clin Transl Oncol. 19:1507–1517. 2017.
View Article : Google Scholar : PubMed/NCBI
|
12
|
Liu R, Cheng J, Chen Y, Wang W, Chen J and
Mao G: Potential role and prognostic importance of dishevelled-2 in
epithelial ovarian cancer. Int J Gynaecol Obstet. 138:304–310.
2017. View Article : Google Scholar : PubMed/NCBI
|
13
|
Zhou G, Ye J, Sun L, Zhang Z and Feng J:
Overexpression of Dishevelled-2 contributes to proliferation and
migration of human esophageal squamous cell carcinoma. J Mol
Histol. 47:287–295. 2016. View Article : Google Scholar : PubMed/NCBI
|
14
|
Hu W, Wang Z, Zhang S, Lu X, Wu J, Yu K,
Ji A, Lu W, Wang Z, Wu J and Jiang C: IQGAP1 promotes pancreatic
cancer progression and epithelial-mesenchymal transition (EMT)
through Wnt/β-catenin signaling. Sci Rep. 9:75392019. View Article : Google Scholar : PubMed/NCBI
|
15
|
Badea L, Herlea V, Dima SO, Dumitrascu T
and Popescu I: Combined gene expression analysis of whole-tissue
and microdissected pancreatic ductal adenocarcinoma identifies
genes specifically overexpressed in tumor epithelia.
Hepatogastroenterology. 55:2016–2027. 2008.PubMed/NCBI
|
16
|
Pei H, Li L, Fridley BL, Jenkins GD,
Kalari KR, Lingle W, Petersen G, Lou Z and Wang L: FKBP51 affects
cancer cell response to chemotherapy by negatively regulating Akt.
Cancer Cell. 16:259–266. 2009. View Article : Google Scholar : PubMed/NCBI
|
17
|
Peng YP, Zhu Y, Yin LD, Zhang JJ, Wei JS,
Liu X, Liu XC, Gao WT, Jiang KR and Miao Y: PEG10 overexpression
induced by E2F-1 promotes cell proliferation, migration, and
invasion in pancreatic cancer. J Exp Clin Cancer Res. 36:302017.
View Article : Google Scholar : PubMed/NCBI
|
18
|
Chun YS, Pawlik TM and Vauthey JN: 8th
Edition of the AJCC cancer staging manual: Pancreas and
Hepatobiliary cancers. Ann Surg Oncol. 25:845–847. 2018. View Article : Google Scholar : PubMed/NCBI
|
19
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
20
|
Aiello NM, Rhim AD and Stanger BZ:
Orthotopic injection of pancreatic cancer cells. Cold Spring Harb
Protoc 2016. pdb.prot078360. 2016. View Article : Google Scholar : PubMed/NCBI
|
21
|
Lu J, Liu X, Liao YP, Salazar F, Sun B,
Jiang W, Chang CH, Jiang J, Wang X, Wu AM, et al: Nano-enabled
pancreas cancer immunotherapy using immunogenic cell death and
reversing immunosuppression. Nat Commun. 8:18112017. View Article : Google Scholar : PubMed/NCBI
|
22
|
Zhou P, Li Y, Li B, Zhang M, Liu Y, Yao Y
and Li D: NMIIA promotes tumor growth and metastasis by activating
the Wnt/beta-catenin signaling pathway and EMT in pancreatic
cancer. Oncogene. 38:5500–5515. 2019. View Article : Google Scholar : PubMed/NCBI
|
23
|
Liu F, Xia Z, Zhang M, Ding J, Feng Y, Wu
J, Dong Y, Gao W, Han Z, Liu Y, et al: SMARCAD1 promotes pancreatic
cancer cell growth and metastasis through Wnt/β-catenin-Mediated
EMT. Int J Biol Sci. 15:636–646. 2019. View Article : Google Scholar : PubMed/NCBI
|
24
|
Luo K, Gu X, Liu J, Zeng G, Peng L, Huang
H, Jiang M, Yang P, Li M, Yang Y, et al: Inhibition of disheveled-2
resensitizes cisplatin-resistant lung cancer cells through
down-regulating Wnt/β-catenin signaling. Exp Cell Res. 347:105–113.
2016. View Article : Google Scholar : PubMed/NCBI
|
25
|
Pulvirenti T, Van Der Heijden M, Droms LA,
Huse JT, Tabar V and Hall A: Dishevelled 2 signaling promotes
self-renewal and tumorigenicity in human gliomas. Cancer Res.
71:7280–7290. 2011. View Article : Google Scholar : PubMed/NCBI
|
26
|
Papadopoulou S and Edlund H: Attenuated
Wnt signaling perturbs pancreatic growth but not pancreatic
function. Diabetes. 54:2844–2851. 2005. View Article : Google Scholar : PubMed/NCBI
|
27
|
Sharma M, Molehin D, Castro-Piedras I,
Martinez EG and Pruitt K: Acetylation of conserved DVL-1 lysines
regulates its nuclear translocation and binding to gene promoters
in triple-negative breast cancer. Sci Rep. 9:162572019. View Article : Google Scholar : PubMed/NCBI
|
28
|
Sharma M, Castro-Piedras I, Simmons GJ and
Pruitt K: Dishevelled: A masterful conductor of complex Wnt
signals. Cell Signal. 47:52–64. 2018. View Article : Google Scholar : PubMed/NCBI
|
29
|
Wong HC, Bourdelas A, Krauss A, Lee HJ,
Shao Y, Wu D, Mlodzik M, Shi DL and Zheng J: Direct binding of the
PDZ domain of Dishevelled to a conserved internal sequence in the
C-terminal region of Frizzled. Mol Cell. 12:1251–1260. 2003.
View Article : Google Scholar : PubMed/NCBI
|
30
|
Paclikova P, Bernatik O, Radaszkiewicz TW
and Bryja V: The N-Terminal part of the Dishevelled DEP domain is
required for Wnt/β-Catenin signaling in mammalian Cells. Mol Cell
Biol. 37:e00145–17. 2017. View Article : Google Scholar : PubMed/NCBI
|
31
|
Gammons MV, Renko M, Johnson CM,
Rutherford TJ and Bienz M: Wnt signalosome assembly by DEP domain
swapping of Dishevelled. Mol Cell. 64:92–104. 2016. View Article : Google Scholar : PubMed/NCBI
|
32
|
Uematsu K, Kanazawa S, You L, He B, Xu Z,
Li K, Peterlin BM, McCormick F and Jablons DM: Wnt pathway
activation in mesothelioma: Evidence of Dishevelled overexpression
and transcriptional activity of beta-catenin. Cancer Res.
63:4547–4551. 2003.PubMed/NCBI
|
33
|
Wang L, Heidt DG, Lee CJ, Yang H, Logsdon
CD, Zhang L, Fearon ER, Ljungman M and Simeone DM: Oncogenic
function of ATDC in pancreatic cancer through Wnt pathway
activation and beta-catenin stabilization. Cancer Cell. 15:207–219.
2009. View Article : Google Scholar : PubMed/NCBI
|
34
|
Gan XQ, Wang JY, Xi Y, Wu ZL, Li YP and Li
L: Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading
to stabilization of beta-catenin-TCF interaction. J Cell Biol.
180:1087–1100. 2008. View Article : Google Scholar : PubMed/NCBI
|
35
|
Itoh K, Brott BK, Bae GU, Ratcliffe MJ and
Sokol SY: Nuclear localization is required for Dishevelled function
in Wnt/beta-catenin signaling. J Biol. 4:32005. View Article : Google Scholar : PubMed/NCBI
|
36
|
Hegazy SA, Alshareef A, Gelebart P, Anand
M, Armanious H, Ingham RJ and Lai R: Disheveled proteins promote
cell growth and tumorigenicity in ALK-positive anaplastic large
cell lymphoma. Cell Signal. 25:295–307. 2013. View Article : Google Scholar : PubMed/NCBI
|
37
|
Lee YN, Gao Y and Wang HY: Differential
mediation of the Wnt canonical pathway by mammalian Dishevelleds-1,
−2, and −3. Cell Signal. 20:443–452. 2008. View Article : Google Scholar : PubMed/NCBI
|
38
|
Tiwari N, Gheldof A, Tatari M and
Christofori G: EMT as the ultimate survival mechanism of cancer
cells. Semin Cancer Biol. 22:194–207. 2012. View Article : Google Scholar : PubMed/NCBI
|
39
|
Geng Y, Ju Y, Ren F, Qiu Y, Tomita Y,
Tomoeda M, Kishida M, Wang Y, Jin L, Su F, et al: Insulin receptor
substrate 1/2 (IRS1/2) regulates Wnt/β-catenin signaling through
blocking autophagic degradation of dishevelled 2. J Biol Chem.
289:11230–11241. 2014. View Article : Google Scholar : PubMed/NCBI
|
40
|
Xu Y, Chang R, Peng Z, Wang Y, Ji W, Guo
J, Song L, Dai C, Wei W and Wu Y: Loss of polarity protein AF6
promotes pancreatic cancer metastasis by inducing Snail expression.
Nat Commun. 6:71842015. View Article : Google Scholar : PubMed/NCBI
|
41
|
Esaki N, Enomoto A, Takagishi M, Mizutani
Y, Iida T, Ushida K, Shiraki Y, Mii S and Takahashi M: The
Daple-CK1epsilon complex regulates Dvl2 phosphorylation and
canonical Wnt signaling. Biochem Biophys Res Commun. 532:406–413.
2020. View Article : Google Scholar : PubMed/NCBI
|