Open Access

Research progress on RNA‑binding proteins in breast cancer (Review)

  • Authors:
    • Wenzhu Zhang
    • Linlin Liu
    • Shengdi Zhao
    • Liang Chen
    • Yuxian Wei
    • Wenlin Chen
    • Fei Ge
  • View Affiliations

  • Published online on: February 14, 2022     https://doi.org/10.3892/ol.2022.13241
  • Article Number: 121
  • Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Breast cancer is the most common malignancy among women, and the abnormal regulation of gene expression serves an important role in its occurrence and development. However, the molecular mechanisms underlying gene expression are highly complex and heterogeneous, and RNA‑binding proteins (RBPs) are among the key regulatory factors. RBPs bind targets in an environment‑dependent or environment‑independent manner to influence mRNA stability and the translation of genes involved in the formation, progression, metastasis and treatment of breast cancer. Due to the growing interest in these regulators, the present review summarizes the most influential studies concerning RBPs associated with breast cancer to elucidate the role of RBPs in breast cancer and to assess how they interact with other key pathways to provide new molecular targets for the diagnosis and treatment of breast cancer.
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April-2022
Volume 23 Issue 4

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Zhang W, Liu L, Zhao S, Chen L, Wei Y, Chen W and Ge F: Research progress on RNA‑binding proteins in breast cancer (Review). Oncol Lett 23: 121, 2022
APA
Zhang, W., Liu, L., Zhao, S., Chen, L., Wei, Y., Chen, W., & Ge, F. (2022). Research progress on RNA‑binding proteins in breast cancer (Review). Oncology Letters, 23, 121. https://doi.org/10.3892/ol.2022.13241
MLA
Zhang, W., Liu, L., Zhao, S., Chen, L., Wei, Y., Chen, W., Ge, F."Research progress on RNA‑binding proteins in breast cancer (Review)". Oncology Letters 23.4 (2022): 121.
Chicago
Zhang, W., Liu, L., Zhao, S., Chen, L., Wei, Y., Chen, W., Ge, F."Research progress on RNA‑binding proteins in breast cancer (Review)". Oncology Letters 23, no. 4 (2022): 121. https://doi.org/10.3892/ol.2022.13241