Open Access

Therapeutic pattern and progress of neoadjuvant treatment for triple‑negative breast cancer (Review)

  • Authors:
    • Yan Xiao
    • Wencheng Gao
  • View Affiliations

  • Published online on: May 19, 2022     https://doi.org/10.3892/ol.2022.13340
  • Article Number: 219
  • Copyright: © Xiao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Triple‑negative breast cancer (TNBC) is a heterogeneous disease, accounting for about 15.0‑20.0% of all breast cancer cases. TNBC is associated with early recurrence and metastasis, strong invasiveness and a poor prognosis. Chemotherapy is currently the mainstay of treatment for TNBC, and achievement of a pathological complete response is closely associated with a long‑term good prognosis. Improving the long‑term prognosis in patients with TNBC is a challenge in breast cancer treatment, and more clinical evidence is needed to guide the choice of treatment strategies. The current study reviews the conventional treatment modality for TNBC and the selection of neoadjuvant chemotherapy (NACT) regimens available. The research progress on optimizing NACT regimens is also reviewed, and the uniqueness of the treatment of this breast cancer subtype is emphasized, in order to provide reference for the clinical practice and research with regard to TNBC treatment.
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July-2022
Volume 24 Issue 1

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Copy and paste a formatted citation
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Spandidos Publications style
Xiao Y and Gao W: Therapeutic pattern and progress of neoadjuvant treatment for triple‑negative breast cancer (Review). Oncol Lett 24: 219, 2022.
APA
Xiao, Y., & Gao, W. (2022). Therapeutic pattern and progress of neoadjuvant treatment for triple‑negative breast cancer (Review). Oncology Letters, 24, 219. https://doi.org/10.3892/ol.2022.13340
MLA
Xiao, Y., Gao, W."Therapeutic pattern and progress of neoadjuvant treatment for triple‑negative breast cancer (Review)". Oncology Letters 24.1 (2022): 219.
Chicago
Xiao, Y., Gao, W."Therapeutic pattern and progress of neoadjuvant treatment for triple‑negative breast cancer (Review)". Oncology Letters 24, no. 1 (2022): 219. https://doi.org/10.3892/ol.2022.13340