Resectability in bronchogenic carcinoma: A single‑center experience

Marie,Mohammed Mowafaq; Jaber,Sabah N.; Ahmed,Okba F.; Kakamad,Fahmi H.; Hama Amin,Bnar J.; Tahir,Soran H.; Salih,Abdulwahid M.; Abdalla,Shalaw H.; Ali,Razhan K.; Rashid,Rezheen J.; Mohammed,Shvan H.; Mustafa,Shevan M.; Ali,Rebwar A.; Rahim,Hawbash M.

doi:10.3892/ol.2023.13805

Resectability in bronchogenic carcinoma: A single‑center experience

Authors:
- Mohammed Mowafaq Marie
- Sabah N. Jaber
- Okba F. Ahmed
- Fahmi H. Kakamad
- Bnar J. Hama Amin
- Soran H. Tahir
- Abdulwahid M. Salih
- Shalaw H. Abdalla
- Razhan K. Ali
- Rezheen J. Rashid
- Shvan H. Mohammed
- Shevan M. Mustafa
- Rebwar A. Ali
- Hawbash M. Rahim
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Affiliations: Department of Surgery, Al Jamhori Teaching Hospital, Mousl 41001, Republic of Iraq, Department of Surgery, Medical City, Baghdad 10011, Republic of Iraq, Department of Surgery, Mousl Cardiac Center, Mousl 41001, Republic of Iraq, Kscien Organization for Scientific Research, University of Sulaimani, Sulaimani 46000, Republic of Iraq, Smart Health Tower, University of Sulaimani, Sulaimani 46000, Republic of Iraq, Department of Oncology, Hiwa Cancer Hospital, Sulaimani 46000, Republic of Iraq, Department of Cardiothoracic and Vascular Surgery, Shar Hospital, Sulaimani 46000, Republic of Iraq
Published online on: April 12, 2023 https://doi.org/10.3892/ol.2023.13805
Article Number: 219
Copyright: © Marie et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Bronchogenic carcinoma comprises >90% of primary lung tumors. The present study aimed to estimate the profile of patients with bronchogenic carcinoma and assess the cancer resectability in newly diagnosed patients. This is a single‑center retrospective review conducted over a period of 5 years. A total of 800 patients with bronchogenic carcinoma were included. The diagnoses were mostly proven with either cytological examination or histopathological diagnosis. Sputum analysis, cytological examination of pleural effusion and bronchoscopic examination were performed. Lymph node biopsy, minimally invasive procedures (mediastinoscopy and video‑assisted thoracoscopic surgery), tru‑cut biopsy or fine‑needle aspiration was used to obtain the samples for diagnosis. The masses were removed by lobectomy and pneumonectomy. The age range was between 22 and 87 years, with a mean age of 62.95 years. Males represented the predominant sex. Most of the patients were smokers or ex‑smokers. The most common symptom was a cough, followed by dyspnea. Chest radiography revealed abnormal findings in 699 patients. A bronchoscopic evaluation was performed for the majority of patients (n=633). Endobronchial masses and other suggestive malignancy findings were present in 473 patients (83.1%) of the 569 who underwent fiberoptic bronchoscopy. Cytological and/or histopathological samples of 581 patients (91.8%) were positive. Small cell lung cancer (SCLC) occurred in 38 patients (4.75%) and non‑SCLC was detected in 762 patients (95.25%). Lobectomy was the main surgical procedure, followed by pneumonectomy. A total of 5 patients developed postoperative complications without any mortality. In conclusion, bronchogenic carcinoma is rapidly increasing without a predilection for sex in the Iraqi population. Advanced preoperative staging and investigation tools are required to determine the rate of resectability.

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