Open Access

Long noncoding RNAs, glucose metabolism and cancer (Review)

  • Authors:
    • Xin-Rui Hou
    • Zhen-Dong Zhang
    • Xiao-Lan Cao
    • Xiao-Ping Wang
  • View Affiliations

  • Published online on: June 22, 2023     https://doi.org/10.3892/ol.2023.13925
  • Article Number: 340
  • Copyright: © Hou et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Cancer is a serious and potentially life‑threatening disease, which, despite numerous advances over several decades, remains a challenge to treat that challenging to detect at an early stage or treat during the later stages. Long noncoding RNAs are >200 nucleotides long and do not possess protein‑coding capacity, instead regulating cellular processes, such as proliferation, differentiation, maturation, apoptosis, metastasis, and sugar metabolism. Several studies have shown the role of lncRNAs and glucose metabolism in regulating several key glycolytic enzymes and the activity of multiple functional signaling pathways during tumor progression. Thus, it is possible to further learn about the effects of lncRNA and glycolytic metabolism on tumor diagnosis, treatment, and prognosis through a thorough investigation of the lncRNA expression profiles and glycolytic metabolism in tumors. This may provide a novel strategy for improving the management of several types of cancer.
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August-2023
Volume 26 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Hou X, Zhang Z, Cao X and Wang X: Long noncoding RNAs, glucose metabolism and cancer (Review). Oncol Lett 26: 340, 2023.
APA
Hou, X., Zhang, Z., Cao, X., & Wang, X. (2023). Long noncoding RNAs, glucose metabolism and cancer (Review). Oncology Letters, 26, 340. https://doi.org/10.3892/ol.2023.13925
MLA
Hou, X., Zhang, Z., Cao, X., Wang, X."Long noncoding RNAs, glucose metabolism and cancer (Review)". Oncology Letters 26.2 (2023): 340.
Chicago
Hou, X., Zhang, Z., Cao, X., Wang, X."Long noncoding RNAs, glucose metabolism and cancer (Review)". Oncology Letters 26, no. 2 (2023): 340. https://doi.org/10.3892/ol.2023.13925