Open Access

Endoscopic transsphenoidal approach in resection of intracranial clivus chondrosarcoma: A case report

  • Authors:
    • Hao Tian Jiang
    • Pan Wang
    • Jun Wei Wang
    • Jie Liu
    • Chao Tang
    • Gang Zhang
    • Jin Yu Pan
    • Hao Fei Geng
    • Nan Wu
  • View Affiliations

  • Published online on: October 3, 2023     https://doi.org/10.3892/ol.2023.14085
  • Article Number: 498
  • Copyright: © Jiang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Intracranial primary chondrosarcomas are rare, accounting for <0.15% of all intracranial tumors, but exhibit a high risk of recurrence. Due to the rarity of this condition, it has proven difficult to establish efficacy‑based treatment guidelines. The present study details a case of clivus chondrosarcoma exhibiting no recurrence following surgical resection using an endoscopic transsphenoidal approach and postoperative adjuvant radiotherapy. A 41‑year‑old female presented with primary symptoms of left eye esotropia, scotoma of the left nasal visual field and double vision. Preoperative cranial magnetic resonance imaging revealed a lesion on the clivus, which was initially diagnosed as chordoma. However, clivus chondrosarcoma was ultimately diagnosed based on intraoperative findings and postoperative histopathology. The tumor was totally resected and 25 doses of adjuvant radiotherapy with planning gross tumor volume (60 Gy) and planning clinical target volume (50 Gy) were administered for 5 weeks. The patient was discharged at 12 days post‑surgery with no obvious postoperative complications. Over the 28‑month follow‑up period, there was no evidence of recurrence, which may be due to the successful use of combined gross total resection and adjuvant radiotherapy. Therefore, surgical resection using an endoscopic transsphenoidal approach and postoperative adjuvant radiotherapy is an effective method for treating intracranial clivus chondrosarcoma.
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November-2023
Volume 26 Issue 5

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Jiang HT, Wang P, Wang JW, Liu J, Tang C, Zhang G, Pan JY, Geng HF and Wu N: Endoscopic transsphenoidal approach in resection of intracranial clivus chondrosarcoma: A case report. Oncol Lett 26: 498, 2023.
APA
Jiang, H.T., Wang, P., Wang, J.W., Liu, J., Tang, C., Zhang, G. ... Wu, N. (2023). Endoscopic transsphenoidal approach in resection of intracranial clivus chondrosarcoma: A case report. Oncology Letters, 26, 498. https://doi.org/10.3892/ol.2023.14085
MLA
Jiang, H. T., Wang, P., Wang, J. W., Liu, J., Tang, C., Zhang, G., Pan, J. Y., Geng, H. F., Wu, N."Endoscopic transsphenoidal approach in resection of intracranial clivus chondrosarcoma: A case report". Oncology Letters 26.5 (2023): 498.
Chicago
Jiang, H. T., Wang, P., Wang, J. W., Liu, J., Tang, C., Zhang, G., Pan, J. Y., Geng, H. F., Wu, N."Endoscopic transsphenoidal approach in resection of intracranial clivus chondrosarcoma: A case report". Oncology Letters 26, no. 5 (2023): 498. https://doi.org/10.3892/ol.2023.14085