Coexistence of small gastrointestinal stromal tumor and pancreatic cancer: A case report and literature review

Chen,Xia; Tan,Yiwei; Gong,An'An

doi:10.3892/ol.2023.14096

Coexistence of small gastrointestinal stromal tumor and pancreatic cancer: A case report and literature review

Authors:
- Xia Chen
- Yiwei Tan
- An'An Gong
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Affiliations: Department of Endocrinology, Yiwu Central Hospital, Yiwu, Zhejiang 322000, P.R. China, Department of Hepatopancreatobiliary Surgery, Yiwu Central Hospital, Yiwu, Zhejiang 322000, P.R. China
Published online on: October 11, 2023 https://doi.org/10.3892/ol.2023.14096
Article Number: 509
Copyright: © Chen et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Small gastrointestinal stromal tumors (GISTs) are rare and malignant tumors that originate in the mesenchymal tissue. Due to their insidious onset and nonspecific symptoms, they are often misdiagnosed, and are generally detected during the diagnosis and treatment of other diseases. The present case report reviewed the treatment process of a patient with a small GIST coexisting with pancreatic cancer who was admitted to the Yiwu Central Hospital (Yiwu, China) in June 2018. The patient was diagnosed and treated comprehensively using a combined approach of urology, and gastrointestinal and hepatobiliary surgery. The present case report provides important clinical insights, which allow for an improved understanding of GIST and provides a reference for clinical treatment.

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1	Blay JY, Kang YK, Nishida T and von Mehren M: Gastrointestinal stromal tumours. Nat Rev Dis Primers. 7:222021. View Article : Google Scholar : PubMed/NCBI
2	Mazur MT and Clark HB: Gastric stromal tumors. Reappraisal of histogenesis. Am J Surg Pathol. 7:507–519. 1983. View Article : Google Scholar : PubMed/NCBI
3	Sikai W: A national study on the incidence rate of gastrointestinal stromal tumors in urban population of China. Chin J Med. 102:4672022.
4	Miettinen M, Sarlomo-Rikala M and Lasota J: Gastrointestinal stromal tumors: Recent advances in understanding of their biology. Hum Pathol. 30:1213–1220. 1999. View Article : Google Scholar : PubMed/NCBI
5	Miettinen M, Majidi M and Lasota J: Pathology and diagnostic criteria of gastrointestinal stromal tumors (GISTs): A review. Eur J Cancer. 38 (Suppl 5):S39–S51. 2002. View Article : Google Scholar : PubMed/NCBI
6	Bejiga G: Pancreatic body cancer presenting with dysphagia and palpable abdominal mass being mistaken for gastric gastrointestinal stromal tumor: ‘Case report’. Int J Surg Case Rep. 92:1068352022. View Article : Google Scholar : PubMed/NCBI
7	Zhijun L, Mi Z and Shangming Y: Clinical analysis of extraabdominal and pelvic metastasis of gastrointestinal stromal tumors. Shenzhen J Integrated Traditional Chin Western Med. 27:143–144. 2017.
8	Wang YP, Li YI and Song C: Clinicopathological features and prognosis of small gastrointestinal stromal tumors outside the stomach. Oncol Lett. 10:2723–2730. 2015. View Article : Google Scholar : PubMed/NCBI
9	Fan X, Han H, Sun Z, Zhang L, Chen G, Mzee SAS, Yang H and Chen J: Prognostic value of bleeding in gastrointestinal stromal tumors: A meta-analysis. Technol Cancer Res Treat. 20:153303382110342592021. View Article : Google Scholar : PubMed/NCBI
10	Hirota S: Differential diagnosis of gastrointestinal stromal tumor by histopathology and immunohistochemistry. Transl Gastroenterol Hepatol. 3:272018. View Article : Google Scholar : PubMed/NCBI
11	Wu CE, Tzen CY, Wang SY and Yeh CN: Clinical diagnosis of gastrointestinal stromal tumor (GIST): From the molecular genetic point of view. Cancers (Basel). 11:6792019. View Article : Google Scholar : PubMed/NCBI
12	Junjie Y, Yehong Y, Jinhua G, et al: A case of giant stromal tumor of the duodenum with cystic transformation. Guangdong Med J. 38:26162017.
13	Arpaci T, Tokat F, Arpaci RB, Akbas T, Ugurluer G and Yavuz S: Primary pericardial extragastrointestinal stromal tumor: A case report and literature review. Oncol Lett. 9:2726–2728. 2015. View Article : Google Scholar : PubMed/NCBI
14	Hu D, Duan Y, Chen Y, Li B, Du Y and Shi S: A case report of gastrointestinal stromal tumor of the duodenum. Am J Transl Res. 15:8279–8285. 2022.PubMed/NCBI
15	Gastrointestinal stromal tumor expert committee of the Chinese Society of Clinical Oncology Chinese Consensus on the Diagnosis and Treatment of Gastrointestinal Stromal Tumors (2017 Edition). Electronic J Comprehensive Tumor Ther. 4:31–43. 2018.
16	Shi P, Zhang J, Li Y and Ma L: Comparative study of ultrasound findings and pathological risk classification of gastrointestinal stromal tumors. Modern Oncol Med. 2795–2797. 2015.(In Chinese).
17	Madhavan A, Phillips AW, Donohoe CL, Willows RJ, Immanuel A, Verril M and Griffin SM: Surgical management of gastric gastrointestinal stromal tumours: Comparison of outcomes for local and radical resection. Gastroenterol Res Pract. 2018:21402532018. View Article : Google Scholar : PubMed/NCBI
18	Masiak-Segit W, Rawicz-Pruszyński K, Skórzewska M and Polkowski WP: Surgical treatment of pancreatic cancer. Pol Przegl Chir. 90:45–53. 2018. View Article : Google Scholar : PubMed/NCBI