Open Access

Influence of tumor mycobiome on cancer pathogenesis (Review)

  • Authors:
    • Weipeng Liu
    • Zongrui Li
    • Xiaopeng Li
    • Haiyang Cao
    • He Jiang
    • Qingbin Niu
    • Baoguang Hu
  • View Affiliations

  • Published online on: November 2, 2023     https://doi.org/10.3892/ol.2023.14128
  • Article Number: 541
  • Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Cancer tissues harbor a large microbiome. There is growing evidence that the tumor microbiome is significantly correlated with the prognosis of cancer patients, but the exact underlying mechanisms have remained elusive. Although the tumor mycobiome is less abundant than the biome of bacteria, it is prevalent in most cancers in humans. The present review describes in detail the impact of the tumor mycobiome on cancer pathogenesis. The tumor mycobiome promotes tumor progression and metastasis by affecting the human immune system, maintaining a pro‑inflammatory environment, producing aflatoxins, attenuating cell adhesion mechanisms and fungal‑bacterial interactions. Furthermore, the tumor mycobiome likewise has great potential for cancer prevention, diagnosis and treatment.
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December-2023
Volume 26 Issue 6

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Liu W, Li Z, Li X, Cao H, Jiang H, Niu Q and Hu B: Influence of tumor mycobiome on cancer pathogenesis (Review). Oncol Lett 26: 541, 2023.
APA
Liu, W., Li, Z., Li, X., Cao, H., Jiang, H., Niu, Q., & Hu, B. (2023). Influence of tumor mycobiome on cancer pathogenesis (Review). Oncology Letters, 26, 541. https://doi.org/10.3892/ol.2023.14128
MLA
Liu, W., Li, Z., Li, X., Cao, H., Jiang, H., Niu, Q., Hu, B."Influence of tumor mycobiome on cancer pathogenesis (Review)". Oncology Letters 26.6 (2023): 541.
Chicago
Liu, W., Li, Z., Li, X., Cao, H., Jiang, H., Niu, Q., Hu, B."Influence of tumor mycobiome on cancer pathogenesis (Review)". Oncology Letters 26, no. 6 (2023): 541. https://doi.org/10.3892/ol.2023.14128